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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Influence of visible light on cutaneous hyperchromias: Clinical efficacy of broad-spectrum sunscreens

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Author(s):
Martini, Ana Paula M. [1] ; Maia Campos, Patricia M. B. G. [1]
Total Authors: 2
Affiliation:
[1] Univ Sao Paulo, Fac Pharmaceut Sci Ribeirao Preto, Ribeirao Preto - Brazil
Total Affiliations: 1
Document type: Journal article
Source: PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE; v. 34, n. 4, p. 241-248, JUL 2018.
Web of Science Citations: 4
Abstract

IntroductionCutaneous hyperchromias are disorders of skin pigmentation involving increased melanin production and its irregular accumulation in skin cells. The use of sunscreens is fundamental for the control of hyperchromias by reducing the stimulation of pigmentation, as melanin synthesis is mainly stimulated by solar radiation. Many studies have demonstrated that visible light can induce significant skin damage. Considering the effects of visible light, effective photoprotection should not be limited only to UV protection but should also involve visible and infrared protection. ObjectiveThe aim of this study was to evaluate the efficacy of UV-VIS sunscreens in protecting skin against damages caused by solar radiation and the influence of visible light on the appearance of cutaneous hyperchromias. MethodsForty volunteers aged 18 to 39years with skin hyperpigmentation participated in the study. To evaluate the efficacy of the formulations developed, the percentage of hyperpigmented area was evaluated using high-resolution imagesVisioface((R)) Quick (Courage-Khazaka, Germany) and the analysis of epidermal pigmentation was performed by RCMVivascope((R)) 1500 (Lucid, USA). Also, the melanin index was determined using the Mexameter((R)) M X16 colorimeter (Courage-Khazaka, Germany). ResultsThe developed formulations were effective in the reduction in melanin index, epidermal pigmentation, and percentage of hyperpigmented area. ConclusionFinally, this study discusses how the combination of UV filters and pigments can protect the skin from solar radiation and reduces skin hyperpigmentations. (AU)

FAPESP's process: 14/26988-5 - Characterization of the skin pigmentation pattern and evaluation of photoprotectors on the reduction of cutaneous hyperchromias
Grantee:Ana Paula Martins Martini
Support Opportunities: Scholarships in Brazil - Scientific Initiation