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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Anti-MOG (Myelin Oligodendrocyte Glycoprotein)-Positive Severe Optic Neuritis with Optic Disc Ischaemia and Macular Star

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Author(s):
Moura, Frederico Castelo [1] ; Sato, Douglas Kazutoshi [2, 3] ; Rimkus, Carolina Medeiros [4] ; Apostolos-Pereira, Samira Luisa [2] ; de Oliveira, Luana Michelli [2] ; Leite, Claudia Costa [4] ; Fujihara, Kazuo [3] ; Ribeiro Monteiro, Mario Luiz [1] ; Callegaro, Dagoberto [2]
Total Authors: 9
Affiliation:
[1] Univ Sao Paulo, Fac Med, Dept Ophthalmol, Rua Mato Grosso 306-414, BR-01239040 Sao Paulo, SP - Brazil
[2] Univ Sao Paulo, Fac Med, Dept Neurol, Sao Paulo - Brazil
[3] Tohoku Univ, Grad Sch Med, Dept Multiple Sclerosis Therapeut, Sendai, Miyagi - Japan
[4] Univ Sao Paulo, Fac Med, Dept Radiol & Oncol, Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: NEURO-OPHTHALMOLOGY; v. 39, n. 6, p. 285-288, 2015.
Web of Science Citations: 2
Abstract

A 44-year-old man presented with severe right visual loss. The right fundus examination showed marked optic disc oedema associated with partial macular star. Serological blood tests for infectious agents were all negative. Serum aquaporin-4 antibody was negative but anti-MOG (myelin oligodendrocyte glycoprotein) was positive. Magnetic resonance revealed extensive lesion in right optic nerve. There was no visual improvement after intravenous therapy. Patient had no further attacks after follow-up. Optic disc oedema with macular star is found in several infectious and non-inflammatory disorders, but it has not been reported in optic neuritis (ON) associated with autoantibodies to myelin oligodendrocyte glycoprotein (anti-MOG). (AU)

FAPESP's process: 14/02010-6 - Cortical graphs and brain disconnectiont in multiple sclerosis
Grantee:Carolina de Medeiros Rimkus
Support type: Scholarships in Brazil - Post-Doctorate