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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Saliva with reduced calcium and phosphorous concentrations: Effect on erosion dental lesions

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Author(s):
Denucci, G. C. [1] ; Mantilla, T. F. [2] ; Amaral, F. L. B. [3] ; Basting, R. T. [3] ; Franca, F. M. G. [3] ; Turssi, C. P. [3]
Total Authors: 6
Affiliation:
[1] Sao Leopoldo Mand Sch Dent, Campinas, SP - Brazil
[2] Univ Sao Paulo, Sch Dent, Dept Restorat Dent, Sao Paulo - Brazil
[3] Sao Leopoldo Mand Inst & Dent Res Ctr, Div Cariol & Restorat Dent, Campinas, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: ORAL DISEASES; v. 24, n. 6, p. 957-963, SEP 2018.
Web of Science Citations: 3
Abstract

ObjectivesTo investigate whether saliva formulations with reduced calcium (Ca) and inorganic phosphorous (Pi) concentration would affect dental erosion caused by hydrochloric acid (HCl). MethodsEnamel and root dentine bovine slabs were embedded, polished, and measured for surface Knoop microhardness (SMH). After reference areas were created, specimens were exposed to HCl solution (0.01M; pH 2; 120s) and immersed in artificial salivas (6hr) containing three different Ca/Pi concentrations (n=15), which simulate serum conditions of normo-, mild, or severe hypocalcemia. The control group was immersed in Ca/Pi-free saliva. The study protocol was carried out 2x/day for 5days. Surface loss of enamel and root dentine was assessed using an optical profilometer, and SMH was remeasured for enamel. ResultsOne-way analysis of variance (p<.001) and Tukey's test showed that enamel loss in groups subjected to artificial salivas that simulated mild or severe hypocalcemia did not differ from that resembling normocalcemia. %SMH was lower when saliva was mildly and normally concentrated in Ca/Pi (p<.001). Root dentine loss was higher in saliva simulating severe hypocalcemia than in those referring to mild, hypo-, and normocalcemia. ConclusionsDepending on the dental substrate, salivary formulations resembling serum hypocalcemia affected surface loss due to erosion and rehardening thereof. (AU)

FAPESP's process: 13/27072-1 - Dental erosion caused by acid from endogenous origin: effect of reduced calcium content in saliva formulations
Grantee:Giovanna Corrêa Denucci
Support Opportunities: Scholarships in Brazil - Scientific Initiation