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In situ effect of chewing gum containning casein phosphopeptide - amorphous calcium phosphate (cpp-acp)on dental erosion

Grant number: 11/16326-7
Support type:Scholarships in Brazil - Master
Effective date (Start): March 01, 2012
Effective date (End): April 30, 2013
Field of knowledge:Health Sciences - Dentistry - Pediatric Dentistry
Principal researcher:Daniela Rios Honório
Grantee:Catarina Ribeiro Barros de Alencar
Home Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil

Abstract

In the last decades researches in dentistry have shown increasing prevalence of dental erosion. Thus many types of treatment are proposed for these lesions and most of them are based on the remineralization of enamel,demineralized by acids not envolving bacterias. One of these elements is the casein phosphopeptide - amorphous calcium phosphate (cpp-acp), commercially named Recaldent©, that when incorporated into the chewing gum has the proposal to enhance the enamel remineralization. The purpose of this study is to assess the effect of CPP-ACP present in the chewing gum on in situ dental erosion. For this purpose, permanent teeth blocks will placed into a palatal appliance used by 12 previously selected volunteers. The trial presents four groups with the following conditions: GI -enamel subjected to erosive challenge untreated, GII - enamel subjected to erosive challenge treated with Trident Total© (CPP-ACP), GIII - enamel subjected to erosive challenge treated with Trident©, GIV - enamel subjected to erosive challenge treated with a unflavored Trident© . The study presents four phases of 7 days with an washout period of 7 days. In each phase the volunteer will immerse the palatal appliance in an acidic beverage 4 times a day for 5 minutes. The enamel changes will be analyzed by surface hardness and profilometry. The results will be submitted to appropriate statistical analysis considering the factor under study (type of treatment for remineralization and type of treatment for erosive cycling, both at three levels). The significance level will be 5%.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
BARROS DE ALENCAR, CATARINA RIBEIRO; DE OLIVEIRA, GABRIELA CRISTINA; MAGALHAES, ANA CAROLINA; RABELO BUZALAF, MARILIA AFONSO; DE ANDRADE MOREIRA MACHADO, MARIA APARECIDA; HONORIO, HEITOR MARQUES; RIOS, DANIELA. In situ effect of CPP-ACP chewing gum upon erosive enamel loss. Journal of Applied Oral Science, v. 25, n. 3, p. 258-264, MAY-JUN 2017. Web of Science Citations: 1.
BARROS DE ALENCAR, CATARINA RIBEIRO; MAGALHAES, ANA CAROLINA; DE ANDRADE MOREIRA MACHADO, MARIA APARECIDA; DE OLIVEIRA, THAIS MARCHINI; HONORIO, HEITOR MARQUES; RIOS, DANIELA. In situ effect of a commercial CPP-ACP chewing gum on the human enamel initial erosion. Journal of Dentistry, v. 42, n. 11, p. 1502-1507, NOV 2014. Web of Science Citations: 17.
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
ALENCAR, Catarina Ribeiro Barros de. Efeito in situ de uma goma de mascar contendo caseína fosfopeptídea - fosfato de cálcio amorfo (CPP-ACP) na erosão dentária. 2013. Master's Dissertation - Universidade de São Paulo (USP). Faculdade de Odontologia de Bauru Bauru.

Please report errors in scientific publications list by writing to: cdi@fapesp.br.