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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effect of desensitizing toothpastes on dentin erosive wear and tubule occlusion. An in situ study

Lopes, Raquel Marianna [1] ; Scaramucci, Tais [1] ; Correa Aranha, Ana Cecilia [1]
Total Authors: 3
[1] Univ Sao Paulo, Sch Dent, Dept Restorat Dent, 2227 Cidade Univ, BR-05508000 Sao Paulo, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: AMERICAN JOURNAL OF DENTISTRY; v. 31, n. 4, p. 177-183, AUG 2018.
Web of Science Citations: 0

Purpose: To evaluate the effect of desensitizing dentifrices on dentin wear and tubule occlusion using a three-phase, single blind, crossover in situ trial. Methods: The dentifrices containing Arginine and calcium carbonate (1,450 ppmF) and Novamin, (1,426 ppmF) were tested in two conditions: A: abrasion and B: erosion/abrasion. A dentifrice without desensitizing agents was used as control (1,450 ppmF). In each study phase, 10 volunteers used intra-oral appliances containing dentin specimens (pre-treated with EDTA, to simulate hypersensitive dentin), which were either submitted to erosion with a cola-like drink (pH 2.6), 4x/day (2 minutes), followed by toothbrushing, using electric toothbrushes, with standard pressure (2x/day, 5 seconds), or toothbrushing only. Dentin surface loss (SL, in am) was determined with optical profilometry at the 3rd and 5th days of cycling. Dentin surface was analyzed with environmental scanning electron microscopy (ESEM), post EDTA and post cycling, and the dentin tubules were counted using Image J software. Data were statistically analyzed (alpha= 0.05). Results: For condition A and B, there were no significant differences in SL among toothpastes in both experimental times. There were also no significant differences between times within groups. For ESEM, in A, Toothpaste with Novamin was the only dentifrice that showed significantly less opened tubules post cycling than post EDTA. In B, Toothpaste with Novamin and control toothpaste presented less opened tubules post cycling. In conclusion, toothbrushing with the tested dentifrices promoted similar levels of dentin loss; however, for tubule occlusion, the toothpaste with Novamin was the only toothpaste effective for both conditions, abrasion and erosion/abrasion. (AU)

FAPESP's process: 15/15629-7 - Analysis of dentine structure loss and tubule occlusion after erosive and abrasive challenge with toothpastes containing desensitizing agents: a randomized in situ study
Grantee:Raquel Marianna Lopes Gaona
Support type: Scholarships in Brazil - Doctorate