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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Near full length genome of a recombinant (E/D) cosavirus strain from a rural area in the central region of Brazil

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Author(s):
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da Costa, Antonio Charlys [1] ; Luchs, Adriana [2] ; de Padua Milagres, Flavio Augusto [3, 4, 5, 6] ; Komninakis, Shirley Vasconcelos [7, 8] ; Gill, Danielle Elise [1] ; Brito Sayao Lobato, Marcia Cristina Alves [4, 6] ; Brustulin, Rafael [4, 5, 6] ; das Chagas, Rogerio Togisaki [4, 6] ; Neves dos Santos Abrao, Maria de Fatima [4, 6] ; de Deus Alves Soares, Cassia Vitoria [4, 6] ; Deng, Xutao [9, 10] ; Sabino, Ester Cerdeira [1, 3] ; Delwart, Eric [9, 10] ; Leal, Elcio [11]
Total Authors: 14
Affiliation:
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[1] Univ Sao Paulo, Inst Trop Med, Sao Paulo - Brazil
[2] Adolfo Lutz Inst, Virol Ctr, Enter Dis Lab, Sao Paulo - Brazil
[3] Univ Sao Paulo, Fac Med, LIM 46, Sao Paulo - Brazil
[4] Secretary Hlth Tocantins, Tocantins - Brazil
[5] Fed Univ Tocantins, Tocantins - Brazil
[6] Publ Hlth Lab Tocantins State LACEN TO, Tocantins - Brazil
[7] Fac Med ABC, Postgrad Program Hlth Sci, Santo Andre - Brazil
[8] Univ Fed Sao Paulo, Retrovirol Lab, Sao Paulo, SP - Brazil
[9] Blood Syst Res Inst, San Francisco, CA - USA
[10] Univ Calif San Francisco, Dept Lab Med, San Francisco, CA 94143 - USA
[11] Fed Univ Para, Inst Biol Sci, Belem, Para - Brazil
Total Affiliations: 11
Document type: Journal article
Source: SCIENTIFIC REPORTS; v. 8, AUG 17 2018.
Web of Science Citations: 1
Abstract

In the present article we report the nearly full length genome of a Cosavirus strain (BRTO-83) isolated from a child with acute gastroenteritis, and who is an inhabitant of a rural area in the central region of Brazil. The sample was previously screened and negative for both: common enteric viruses (i.e. rotavirus and norovirus), bacteria, endoparasites and helminthes. Evolutionary analysis and phylogenetic inferences indicated that the Brazilian BRTO-83 Cosavirus strain was a recombinant virus highly related to the E/D recombinant NG385 strain (Genbank JN867757), which was isolated in Nigeria from an acute flaccid paralysis patient. This is the first report of a recombinant E/D Cosavirus strain detected in Brazil, and the second genome described worldwide. Further surveillance and molecular studies are required to fully understand the epidemiology, distribution and evolution of the Cosavirus. (AU)

FAPESP's process: 15/12944-9 - Investigating the evoltution of animal rotavirus strains infecting humans
Grantee:Adriana Luchs
Support type: Regular Research Grants
FAPESP's process: 17/00021-9 - Viral metagenomics to track, explain and predict the transmission and spatiotemporal spread of Dengue and Chikungunya viruses in Brazil
Grantee:Antonio Charlys da Costa
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 16/01735-2 - Viral metagenomics to track, explain and predict the transmission and spatiotemporal spread of Dengue and Chikungunya viruses in Brazil
Grantee:Ester Cerdeira Sabino
Support type: Regular Research Grants