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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Cu-Catalyzed Decarboxylative Borylation

Full text
Author(s):
Wang, Jie [1] ; Shang, Ming [1] ; Lundberg, Helena [1] ; Feu, Karla S. [1] ; Hecker, Scott J. [2] ; Qin, Tian [1] ; Blackmond, Donna G. [1] ; Baran, Phil S. [1]
Total Authors: 8
Affiliation:
[1] Scripps Res Inst TSRI, Dept Chem, North Torrey Pines Rd, La Jolla, CA 92037 - USA
[2] Medicines Co, 3013 Sci Pk Rd, San Diego, CA 92121 - USA
Total Affiliations: 2
Document type: Journal article
Source: ACS CATALYSIS; v. 8, n. 10, p. 9537-9542, OCT 2018.
Web of Science Citations: 32
Abstract

A simple method for the conversion of carboxylic acids to boronic esters via redox-active esters (RAEs) is reported using copper catalysis. The scope of this transformation is broad, and compared with the known protocols available, it represents the most inexpensive, rapid, and operationally simple option. In addition to a full exploration of the scope, a kinetic study was performed to elucidate substrate and reagent concentration dependences. (AU)

FAPESP's process: 17/08128-7 - Total Synthesis of Eremantholide A and C
Grantee:Karla Santos Feu
Support Opportunities: Scholarships abroad - Research Internship - Post-doctor