Transcriptome datasets of macrophages infected with different strains of Leptospira spp

Author(s)

de Araujo Junior, Erivelto Correa ^[1] ; Garcia, Leandro Encarnacao ^[1] ; Melo, Larissa Martins ^[2] ; Bragato, Jaqueline Poleto ^[2] ; Felix de Lima, Valeria Marcal ^[2] ; Peiro, Juliana Regina ^[2] ; Lopes, Flavia Lombardi ^[1] ; Marinho, Marcia ^[1]

Affiliation

^[1] Sao Paulo State Univ Unesp, Dept Support Prod & Anim Hlth, Sch Vet Med, Aracatuba, SP - Brazil

^[2] Sao Paulo State Univ Unesp, Dept Clin Surg & Anim Reprod, Sch Vet Med, Aracatuba, SP - Brazil

• Document type: Journal article
• Source: DATA IN BRIEF; v. 16, p. 1044-1050, FEB 2018.
• Web of Science Citations: 0

Abstract

The datasets reported herein provide information about micro array experiment of macrophage cell line J774A.1 infected with three different strains of Leptospira spp. Transcriptomic profiles were generated using Affymetrix (R) Mouse Gene 2.1 ST Array Strip. Data was normalized and statically process, p-value < 0.01, FDR < 0.05 and log2 fold change (+/- 2). The microarray raw data are available in Gene Expression Omnibus (GEO) under accession number GSE105141. (C) 2018 Published by Elsevier Inc. (AU)

• FAPESP's process: 14/20719-2 - Profile of macrophage activity in vitro against the virulent, attenuated and saprophytic Leptospira spp. sample
• Grantee: Márcia Marinho
• Support Opportunities: Regular Research Grants
• FAPESP's process: 15/14229-5 - Characterization of the microtranscriptoma of macrophages in response to virulent, attenuated and saprophytic strains of Leptospira spp
• Grantee: Flavia Lombardi Lopes
• Support Opportunities: Regular Research Grants