Bioaccumulation and acute toxicity of As(III) and As(V) in Nile tilapia (Oreochromis niloticus)

Author(s)

Ferreira, Nathalia S. ^[1] ; Oliveira, Luciano H. B. ^[1] ; Agrelli, Vitor ^[1] ; de Oliveira, Aline F. ^{[2, 3]} ; Nogueira, Ana R. A. ^[3] ; Oliveira, Andrea ^[4] ; Gonzalez, Mario H. ^[1]

Affiliation

^[1] Sao Paulo State Univ, Natl Inst Alternat Technol Detect Toxicol Evaluat, UNESP, INCT, DATREM, Dept Chem & Environm Sci, BR-15054000 Sao Jose Do Rio Preto, SP - Brazil

^[2] Univ Fed Sao Carlos, Dept Chem, Grp Appl Instrumental Anal, BR-13565905 Sao Carlos, SP - Brazil

^[3] EMBRAPA, Embrapa Pecuaria Sudeste, BR-13560970 Sao Carlos, SP - Brazil

^[4] Univ Fed Parana, Chem Dept, BR-81531980 Curitiba, PR - Brazil

• Document type: Journal article
• Source: Chemosphere; v. 217, p. 349-354, FEB 2019.
• Web of Science Citations: 3

Abstract

The distribution of arsenic in the different tissues of tilapia fish is determined by the exposure time and the depuration rate. The mechanisms of toxicity/carcinogenicity depend on the arsenic species involved in the biotransformation processes. After a 7-day exposure period, the accumulation of inorganic arsenic (iAs) in the tilapia tissues studied was in the order: liver > stomach > gills > muscles. In bioaccumulation assays, the values of the organ uptake constant (k(a)) ranged from 0.06 to 0.51 mLg(-1) d(-1), while the depuration rate constant (k(d)) values were in the range 0.03-1.15 d(-1). Higher iAs bioaccumulation factor (BCF) values were observed for the stomach (3.1 mL g(-1)) and the liver (1.6 mL g(-1)), reflecting their high capacity to accumulate iAs species. These organs act as long-term storage sites for iAs, following chronic exposure. The LC50 values were determined considering the average iAs concentration and the cumulative fish mortality. For As(III), the LC50 values indicated fish mortality at concentrations above 30 mg L-1. The fish showed greater tolerance to exposure to As(V), compared to As(III), with fish mortality after the second day of exposure requiring an As(V) concentration 7-fold higher than As(III). (C) 2018 Elsevier Ltd. All rights reserved. (AU)

• FAPESP's process: 17/18531-3 - Green analytical chemistry: from sample preparation to trace element determinations by inductively coupled plasma mass spectrometry (ICP-MS)
• Grantee: Mario Henrique Gonzalez
• Support Opportunities: Regular Research Grants
• FAPESP's process: 16/05079-2 - Bioacumulation of As in tilápia (Oreochromis nilóticus): fractionation of as inorganic species
• Grantee: Nathalia dos Santos Ferreira
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 16/24868-8 - Study of acute toxicity of inorganic arsenic (As-i) in tilapia (Oreochromis niloticus)
• Grantee: Vitor Agrelli Fernandes
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 15/08873-9 - Assessment of arsenic's bioaccumulation and associated risks from fish consumption in Brazil
• Grantee: Mario Henrique Gonzalez
• Support Opportunities: Regular Research Grants