Impact of training at ventilatory threshold on cardiopulmonary and functional capacity in overweight patients with chronic kidney disease

Author(s)

Danilo Takashi Aoike ^[1] ; Flavia Baria ^[2] ; Mariana Leister Rocha ^[3] ; Maria Ayako Kamimura ^[4] ; Marco Túlio de Mello ^[5] ; Sergio Tufik ^[6] ; Adriano Ammirati ^[7] ; Lilian Cuppari

Affiliation

^[1] Universidade Federal de São Paulo

^[2] Universidade Federal de São Paulo

^[3] Universidade Federal de São Paulo

^[4] Universidade Federal de São Paulo

^[5] Universidade Federal de São Paulo

^[6] Universidade Federal de São Paulo

^[7] UNIFESP. Fundação Oswaldo Ramos

• Document type: Journal article
• Source: J. Bras. Nefrol.; v. 34, n. 2, p. 139-147, 2012-06-00.

Abstract

INTRODUCTION: Chronic kidney disease (CKD) and obesity are both associated with reduced physical capacity. The potential benefit of aerobic training on physical capacity has been recognized. The exercise intensity can be established using different methods mostly subjective or indirect. Ventilatory threshold (VT) is a direct and objective method that allows prescribing exercise intensity according to individual capacity. OBJECTIVES: To evaluate the impact of aerobic training at VT intensity on cardiopulmonary and functional capacities in CKD patients with excess of body weight. METHODS: Ten CKD patients (eight men, 49.7 ± 10.1 years; BMI 30.4 ± 3.5 kg/m², creatinine clearance 39.4 ± 9.8 mL/min/1.73 m²) underwent training on a treadmill three times per week during 12 weeks. Cardiopulmonary capacity (ergoespirometry), functional capacity and clinical parameters were evaluated. RESULTS: At the end of 12 weeks, VO2PEAK increased by 20%, and the speed at VO2PEAK increased by 16%. The training resulted in improvement in functional capacity tests, such as six-minute walk test (9.2%), two-minute step test (20.3%), arm curl test (16.3%), sit and stand test (35.7%), and time up and go test (15.3%). In addition, a decrease in systolic and diastolic blood pressures was observed despite no change in body weight, sodium intake and antihypertensive medication. CONCLUSION: Aerobic exercise performed at VT intensity improved cardipulmonary and functional capacities of overweight CKD patients. Additional benefit on blood pressure was observed. These results suggest that VT can be effectively applied for prescribing exercise intensity in this particular group of patients. (AU)

• FAPESP's process: 09/14786-0 - Effects of a home-based aerobic training program in relation to a supervised training on physical functioning, nutritional and cardiometabolic parameters in overweight or obese chronic kidney disease patients
• Grantee: Lilian Cuppari
• Support Opportunities: Regular Research Grants