Synthesis of bimodal molecules for photodynamic inactivation of resistant bacteria...
| Full text | |
| Author(s): |
Total Authors: 4
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| Affiliation: | [1] Univ Estadual Campinas, Inst Chem, Biol Chem Lab, BR-13083970 Campinas, SP - Brazil
[2] Univ Coll Dublin, Sch Bioproc & Chem Engn, Dublin D04 V1W8 - Ireland
Total Affiliations: 2
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| Document type: | Review article |
| Source: | ANTIBIOTICS-BASEL; v. 7, n. 3 SEP 2018. |
| Web of Science Citations: | 11 |
| Abstract | |
Multidrug-resistant bacteria (MDRB) are extremely dangerous and bring a serious threat to health care systems as they can survive an attack from almost any drug. The bacteria's adaptive way of living with the use of antimicrobials and antibiotics caused them to modify and prevail in hostile conditions by creating resistance to known antibiotics or their combinations. The emergence of nanomaterials as new antimicrobials introduces a new paradigm for antibiotic use in various fields. For example, silver nanoparticles (AgNPs) are the oldest nanomaterial used for bactericide and bacteriostatic purposes. However, for just a few decades these have been produced in a biogenic or bio-based fashion. This review brings the latest reports on biogenic AgNPs in the combat against MDRB. Some antimicrobial mechanisms and possible silver resistance traits acquired by bacteria are also presented. Hopefully, novel AgNPs-containing products might be designed against MDR bacterial infections. (AU) | |
| FAPESP's process: | 15/12534-5 - Study on the supramolecular interactions in silver nanoparticles and their antimicrobial activity |
| Grantee: | Caio Henrique Nasi de Barros |
| Support type: | Scholarships in Brazil - Master |
| FAPESP's process: | 14/50867-3 - INCT 2014: National Institute of Science and Technology in Bioanalysis |
| Grantee: | Lauro Tatsuo Kubota |
| Support type: | Research Projects - Thematic Grants |