| Full text | |
| Author(s): |
Glaucie Jussilane Alves
;
João Palermo-Neto
Total Authors: 2
|
| Document type: | Journal article |
| Source: | Revista Brasileira de Psiquiatria; v. 29, n. 4, p. 363-369, 2007-08-03. |
| Abstract | |
OBJECTIVE: Several papers arriving from the neuroimmunomodulation field are showing the relevant relationships between the nervous and the immune systems. A review of studies was carried out to describe the bases of the studies on neuroimmunomodulation. EXPERIMENTAL MODELS: It is clear nowadays that emotional states such as anxiety and depression change immune system activity, an affect also observed after both stress and use of nervous system acting drugs. SICK BEHAVIOR: The behavior displayed by sick organisms might be thought as being a consequence of homeostatic strategies. POSSIBLE MECHANISM OF THE ACTION BY MEANS OF IMMUNE SYSTEM TO NERVOUS SYSTEM: A very big emphasis is being given to Hipothalamus-pituitary-adrenal axis, simpathetic nervous system and cytokines participation on nervous system and immune system relationships. CONCLUSION: The present revision intend to show some essential studies in the neuroimmunomodulation field; it makes a critical analysis of the mutual relationships between nervous system and immune system. (AU) | |
| FAPESP's process: | 04/14128-0 - Neuroimmunomodulation: effects of drugs, stress and cytocines on central nervous and immune systems bidirectional relationships |
| Grantee: | João Palermo Neto |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 99/04228-7 - Neuroimmunomodulation: effects of stress and central nervous system acting drugs on immune/inflamatory response |
| Grantee: | João Palermo Neto |
| Support Opportunities: | Research Projects - Thematic Grants |