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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Profile of immunoglobulins, clinical and bacteriological cure after different treatment routes of clinical bovine mastitis

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Author(s):
M.G.B. Lima [1] ; M.G. Blagitz [2] ; F.N. Souza [3] ; E.M.R. Sanchez [4] ; C.F. Batista [5] ; H.G. Bertagnon ; S.A. Diniz [7] ; M.X. Silva [8] ; A.M.M.P. Della Libera [9]
Total Authors: 9
Affiliation:
[1] Universidade de São Paulo - Brasil
[2] Universidade de São Paulo - Brasil
[3] Universidade de São Paulo - Brasil
[4] Universidade de São Paulo - Brasil
[5] Universidade de São Paulo - Brasil
[7] Universidade Federal de Minas Gerais - Brasil
[8] Universidade Federal de Minas Gerais - Brasil
[9] Universidade de São Paulo - Brasil
Total Affiliations: 9
Document type: Journal article
Source: Arquivo Brasileiro de Medicina Veterinária e Zootecnia; v. 70, n. 4, p. 1141-1149, 2018-08-00.
Abstract

ABSTRACT The present study aimed to evaluate the profile of immunoglobins profile, clinical and bacteriological cure after different treatment routes of clinical bovine mastitis. Here, 30 Holstein cows with clinical mastitis in one quarter were uniformly divided into: 10 dairy cows that received 8.5mg of cefquinome sulphate administrated intramammarily during three consecutive milkings and 2.5mg/kg of enrofloxacin administrated parenterally during three consecutive days (Group 1); 10 dairy cows that received 8.5mg of cefquinome sulphate administrated intramammarily during three consecutive milkings (Group 2); and 10 dairy cows that received 2.5mg/kg of enrofloxacin administrated parenterally during three consecutive days (Group 3). Milk samples for somatic cell count, California Mastitis Test (CMT), bacteriological culture and quantification of IgG1, IgG2, IgM and IgA were collected before antimicrobial treatment, and after two, five and 12 days after the antimicrobial treatment. The combined treatment was more effective in the clinical cure rate, reduction of somatic cell count and CMT scores. Furthermore, the results demonstrated that milk concentration of different Igs classes were not related to prognosis of bovine clinical mastitis, and then cannot be considered as robust markers associated with clinical and bacteriological cures. (AU)

FAPESP's process: 12/00008-9 - Profile of cytokines in predicting bovine mastitis following antibiotic therapy
Grantee:Alice Maria Melville Paiva Della Libera
Support Opportunities: Regular Research Grants