| Full text | |
| Author(s): |
Amanda Tavares Pinheiro
[1]
;
Roberto Antonio Araújo Costa
[2]
;
Joelcio Francisco Abbade
[3]
;
Cláudia Garcia Magalhães
[4]
;
Gláucia Maria Ferreira da Silva Mazeto
[5]
Total Authors: 5
|
| Affiliation: | [1] Universidade Estadual Paulista Júlio de Mesquita Filho. Faculdade de Medicina de Botucatu. Departamento de Pediatria - Brasil
[2] Universidade Estadual Paulista Júlio de Mesquita Filho. Faculdade de Medicina de Botucatu. Departamento de Ginecologia e Obstetrícia - Brasil
[3] Universidade Estadual Paulista Júlio de Mesquita Filho. Faculdade de Medicina de Botucatu. Departamento de Ginecologia e Obstetrícia - Brasil
[4] Universidade Estadual Paulista Júlio de Mesquita Filho. Faculdade de Medicina de Botucatu. Departamento de Ginecologia e Obstetrícia - Brasil
[5] Universidade Estadual Paulista Júlio de Mesquita Filho. Faculdade de Medicina de Botucatu. Departamento de Clínica Médica
Total Affiliations: 5
|
| Document type: | Journal article |
| Source: | Revista Brasileira de Ginecologia e Obstetrícia; v. 30, n. 9, p. 452-458, 2008-09-00. |
| Abstract | |
PURPOSE: to evaluate the experience of Hospital das Clínicas da Faculdade de Medicina de Botucatu da Universidade Estadual Paulista "Júlio de Mesquita Filho", in the follow-up of pregnant women with hyperthyroidism. METHODS: Sixty patients, divided in groups with compensated hyperthyroidism (CHG=24) and with uncompensated hyperthyroidism (UHG=36) were retrospectively studied and compared concerning clinical-laboratorial characteristics and intercurrences. The t-Student test, contingency tables, multiple linear regression and multiple logistic regression with significance level at 5.0% were used. RESULTS: propylthiouracil (PTU) was used by 94.0% of UHG and by 42.0% of CHG (p<0.0001); maternal complications close to delivery have occurred in 20.6% of UHG and in 11.8% of CHG, and UHG presented three fetal deaths, influenced by the mother age, higher level of T4L (lT4L) and of PTU dose (PTUd) in the third trimester (p=0.007); restriction of intra-uterine growth, influenced by lT4L and PTUd in the third trimester has occurred in nine UHG and in three CHG cases, and oligoamnios has occurred in 12 patients (83.3% of UGH and 16.7% of CGH), influenced by age and lT4L in the third trimester (p=0.04); the gestational age at delivery was 34.4±4.6 weeks in UHG and 37.0±2.5 in CHG, influenced by the T4Ll in the third trimester (p<0.05). CONCLUSIONS: the UHG has presented less satisfactory results than CHG, influenced by high lT4L and PTUd in the third trimester, and by more advanced age of some pregnant women. (AU) | |