Study of the profile of behavioral problems and quality of life indexes in a pediatric cohort of monosymptomatic enuresis

Author(s)

Sousa e Silva, Guilherme Jorge ^{[1, 2]} ; Fagundes Sammour, Simone Nascimento ^{[2, 3]} ; Ferraro, Alexandre Archanjo ^{[1, 2]} ; Kalika Koch, Vera Hermina ^{[4, 2]}

Affiliation

^[1] Univ Sao Paulo, Fac Med, Sao Paulo, SP - Brazil

^[2] Univ Sao Paulo, Fac Med, Postgrad Program, Pediat Dept, Sao Paulo, SP - Brazil

^[3] Univ Sao Paulo, Fac Med, Dept Pediat, Hosp Clin, Inst Crianca ICr, Sao Paulo, SP - Brazil

^[4] Univ Sao Paulo, Fac Med, Dept Pediat, Sao Paulo, SP - Brazil

• Document type: Journal article
• Source: Jornal de Pediatria; v. 95, n. 2, p. 188-193, MAR-APR 2019.
• Web of Science Citations: 1

Abstract

Objective: To evaluate and correlate, before and after the therapeutic intervention, the behavioral problem scores evaluated by the CBCL/6-18 questionnaire and the quality of life indexes evaluated by the PedsQL (TM) 4.0 in patients with monosymptomatic nocturnal enuresis. Method: After the initial evaluation and completion of the CBCL/6-18 questionnaire, a multidisciplinary evaluation and completion of the PedsQL (TM) 4.0 questionnaire was performed. Of the initially evaluated 140 children and adolescents aged 6-16 years, 58 were excluded due to nonmonosymptomatic enuresis or associated comorbidities. Of the initially included 82 patients, who were randomized to three treatment groups, 59 completed the CBCL/6-18 and PedsQL (TM) 4.0 questionnaires at the end of the treatment and were included in this study. The alpha error was set at 5% for ruling out the null hypothesis. Results: Of the total of 59 participants, 45.8% responded with total success, 23.7% were partially successful, 23.7% did not reach the improvement criteria, and 6.8% gave up the treatment. There was a significant increase in quality of life indexes and a reduction of post-intervention behavioral problem scores, in the three proposed modalities, in patients who had a total or partial response to treatment. There was no correlation between higher scores of pre-treatment behavior problems and therapeutic failure. Conclusions: Only the participants who successfully responded to interventions showed improvement in quality of life and behavioral problems, which indicates that enuresis is a primary problem that has a negative impact on these parameters. The authors suggest that it is possible to achieve success in the treatment of monosymptomatic enuresis, even in patients with high pre-intervention behavioral problem scores. (C) 2018 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. (AU)

• FAPESP's process: 11/17589-1 - Pediastric monosymptomatic nocturnal eEuresis: transdisciplinary evaluation and study of intervention-related changes in polysomnography
• Grantee: Vera Hermina Kalika Koch
• Support Opportunities: Regular Research Grants