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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The Acre Project: the epidemiology of malaria and arthropod-borne virus infections in a rural Amazonian population

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Author(s):
Mônica da Silva-Nunes ; Rosely dos Santos Malafronte ; Bruna de Almeida Luz [3] ; Estéfano Alves de Souza [4] ; Lívia Carício Martins [5] ; Sueli Guerreiro Rodrigues [6] ; Jannifer Oliveira Chiang [7] ; Pedro Fernando da Costa Vasconcelos [8] ; Pascoal Torres Muniz ; Marcelo Urbano Ferreira
Total Authors: 10
Document type: Journal article
Source: Cadernos de Saúde Pública; v. 22, n. 6, p. 1325-1334, 2006-06-00.
Abstract

The authors describe the baseline malaria prevalence and arbovirus seroprevalence among 467 subjects in an ongoing cohort study in rural Amazonia. Most subjects (72.2%) reported one or more previous episodes of malaria, and 15.6% had been hospitalized for malaria, but only 3.6% of individuals five years or older had malaria parasites detected by microscopy (10 with Plasmodium vivax and 4 with P. falciparum). Antibodies to Alphavirus, Orthobunyavirus, and/or Flavivirus were detected by hemagglutination inhibition (HI) in 42.6% of subjects aged five years or older, with a higher seropositivity rate among males (49.2%) than females (36.2%). Since 98.9% of subjects had been immunized for yellow fever, the presence of cross-reactive antibodies to dengue and other Flaviviruses cannot be ruled out, but at least 12 subjects (3.3%) with IgM antibodies to dengue virus detected by ELISA had a putative recent exposure to this virus. (AU)