| Full text | |
| Author(s): Show less - |
Psaltikidis, Eliane Molina
[1, 2, 3]
;
da Silva, Everton Nunes
[4]
;
Moretti, Maria Luiza
[2, 5]
;
Trabasso, Plinio
[2, 5]
;
Bello Stucchi, Raquel Silveira
[6, 5]
;
Aoki, Francisco Hideo
[5]
;
de Oliveira Cardoso, Luis Gustavo
[2]
;
Hofling, Christian Cruz
[2]
;
Bachur, Luis Felipe
[2]
;
Ponchet, Danilo da Fontoura
[6]
;
Ceccato Colombrini, Maria Rosa
[6]
;
Tozzi, Cintia Soarez
[6]
;
Ramos, Rosana Fins
[6]
;
Queiroz Costa, Sandra Mara
[6]
;
Resende, Mariangela Ribeiro
[2, 3, 5]
Total Authors: 15
|
| Affiliation: | [1] Univ Estadual Campinas, Sch Med Sci, Campinas, SP - Brazil
[2] Univ Estadual Campinas, Clin Hosp, Hosp Epidemiol Dept, Campinas, SP - Brazil
[3] Univ Estadual Campinas, Clin Hosp, Hlth Technol Assessment Dept, Campinas, SP - Brazil
[4] Univ Brasilia, Fac Ceilandia, Brasilia, DF - Brazil
[5] Univ Estadual Campinas, Sch Med Sci, Dept Internal Med, Div Infect Dis, Campinas, SP - Brazil
[6] Univ Estadual Campinas, Day Hosp, Clin Hosp, Campinas, SP - Brazil
Total Affiliations: 6
|
| Document type: | Journal article |
| Source: | EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH; v. 19, n. 3, p. 341-352, MAY 4 2019. |
| Web of Science Citations: | 0 |
| Abstract | |
Background: Outpatient parenteral antimicrobial therapy (OPAT) has been used for decades in different countries to reduce hospitalization rates, with favorable clinical and economic outcomes. This study assesses the cost-utility of OPAT compared to inpatient parenteral antimicrobial therapy (IPAT) from the perspective of a public university hospital and the Brazilian National Health System (Unified Health System -SUS). Methods: Prospective study with adult patients undergoing OPAT at an infusion center, compared to IPAT. Clinical outcomes and quality-adjusted life year (QALY) were assessed, as well as a micro-costing. Cost-utility analysis from the hospital and SUS perspectives were conducted by means of a decision tree, within a 30-day horizon time. Results: Forty cases of OPAT (1112 days) were included and monitored, with a favorable outcome in 97.50%. OPAT compared to IPAT generated overall savings of 31.86% from the hospital perspective and 26.53% from the SUS perspective. The intervention reduced costs, with an incremental cost-utility ratio of -44,395.68/QALY for the hospital and -48,466.70/QALY for the SUS, with better cost-utility for treatment times greater than 14 days. Sensitivity analysis confirmed the stability of the model. Conclusion: Our economic assessment demonstrated that, in the Brazilian context, OPAT is a cost-saving strategy both for hospitals and for the SUS. (AU) | |
| FAPESP's process: | 14/50045-3 - Cost-effectiveness of Outpatient Parenteral Antimicrobial Therapy (OPAT) program based on day-hospital patients of Public Health Brazilian System |
| Grantee: | Mariângela Ribeiro Resende |
| Support Opportunities: | Research Grants - Research in Public Policies for the National Health Care System (PP-SUS) |