| Full text | |
| Author(s): Show less - |
Carvalho, Carolina Muniz
[1, 2, 3]
;
Pan, Pedro M.
[1, 2]
;
Ota, Vanessa K.
[2, 3]
;
Spindola, Leticia M.
[1, 2, 3]
;
Xavier, Gabriela
[2, 3]
;
Santoro, Marcos L.
[1, 2, 3]
;
Mazzotti, Diego R.
[4]
;
Pellegrino, Renata
[5]
;
Hakonarson, Hakon
[5]
;
Rohde, Luis Augusto
[6]
;
Miguel, Euripedes Constantino
[7]
;
Gadelha, Ary
[1, 2]
;
Bressan, Rodrigo A.
[1, 2]
;
Belangero, Sintia I.
[1, 2, 3]
Total Authors: 14
|
| Affiliation: | [1] Univ Fed Sao Paulo, Dept Psychiat, Sao Paulo - Brazil
[2] Univ Fed Sao Paulo, Interdisciplinary Lab Clin Neurosci LINC, Sao Paulo - Brazil
[3] Univ Fed Sao Paulo UNIFESP, Dept Morphol & Genet, Genet Div, Sao Paulo - Brazil
[4] Univ Penn, Ctr Sleep & Circadian Neurobiol, Philadelphia, PA 19104 - USA
[5] Childrens Hosp Philadelphia, Lab Ctr Appl Genom, Philadelphia, PA 19104 - USA
[6] Univ Fed Rio Grande do Sul, Dept Psychiat, Porto Alegre, RS - Brazil
[7] Univ Sao Paulo, Fac Med, Dept Psychiat, Sao Paulo - Brazil
Total Affiliations: 7
|
| Document type: | Journal article |
| Source: | PSYCHIATRY RESEARCH; v. 273, p. 575-577, MAR 2019. |
| Web of Science Citations: | 0 |
| Abstract | |
We evaluated the effects of the interaction between child maltreatment (CM) and single nucleotide polymorphisms (SNPs) on development of mental disorders (MD) and psychopathology. We genotyped 720 individuals from a Brazilian community school-based prospective study, focusing on SNPs in 21 genes known to be associated with mental disorders. CM was assessed via a multi-informant-measure, which was previously validated. To test G x CM, we used linear or logistic models depending on variable evaluated (MD or dimensional psychopathology). After Bonferroni multiple comparison correction, we did not find any statistically significant association of G x CM with either MD or psychopathology. (AU) | |
| FAPESP's process: | 08/57896-8 - National Institute for Developmental Psychiatry |
| Grantee: | Eurípedes Constantino Miguel Filho |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 14/50917-0 - INCT 2014: developmental psychiatry for children and adolescents |
| Grantee: | Eurípedes Constantino Miguel Filho |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 14/07280-1 - Search for genetic markers of risk, progression and response to treatment |
| Grantee: | Síntia Iole Nogueira Belangero |
| Support Opportunities: | Regular Research Grants |