Silica modified with polymeric amphiphilic nanoparticles as first dimension for multidimensional separation techniques

Author(s)

Franco, Maraissa S. ^[1] ; Padovan, Rodrigo N. ^[1] ; Fumes, Bruno H. ^[1] ; Palmer, Christopher P. ^[2] ; McGettrick, Julie R. ^[2] ; Lancas, Fernando M. ^[1]

Affiliation

^[1] Univ Sao Paulo, Inst Chem Sao Carlos, Postal Code 780, BR-13560970 Sao Carlos, SP - Brazil

^[2] Univ Montana, Dept Chem & Biochem, Missoula, MT 59812 - USA

• Document type: Journal article
• Source: Journal of Chromatography A; v. 1597, p. 149-158, JUL 19 2019.
• Web of Science Citations: 0

Abstract

This paper addresses the evaluation of a new amphiphilic nanoparticle supported on silica and its application as sorbent in on-line solid phase extraction. The investigated sorbent material is a copolymer composed by {[}2-(Acryloyloxy) ethyl] trimethylammonium chloride (block A) and butyl acrylate (block B) prepared by reversible addition-fragmentation chain transfer. After polymerization the nanoparticles were adsorbed into silica surface by electrostatic attraction providing to the sorbent both, apolar and polar characteristics. After the fundamental studies to understand the main features of the synthesized nanoparticles supported on silica, this sorbent material was packed into an extraction column. This column was connected on line with liquid chromatography-tandem mass spectrometry and utilized for automated online determination of several analytes as Ochratoxin A, azoxystrobin, cyproconazole and difenoconazole, in wine and water samples. (C) 2019 Published by Elsevier B.V. (AU)

• FAPESP's process: 17/02147-0 - Single drop chromatography and its coupling to mass spectrometry: instrumental strategies, development of materials, automation and analytical applications
• Grantee: Fernando Mauro Lanças
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 15/15462-5 - Employment of graphene as sorbent in miniaturized sample preparation techniques.
• Grantee: Bruno Henrique Fumes
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 14/07347-9 - Development of novel materials and devices for miniaturized sample preparation techniques in the area of food safety
• Grantee: Fernando Mauro Lanças
• Support Opportunities: Regular Research Grants
• FAPESP's process: 15/03998-8 - Development, characterization and application of novel micro-extraction techniques based on amphophilic ionic polymers and polymeric nanoparticles
• Grantee: Fernando Mauro Lanças
• Support Opportunities: Research Grants - Visiting Researcher Grant - International