| Full text | |
| Author(s): |
Antunes, Barbara Moura
[1]
;
Rossi, Fabricio Eduardo
[2, 3]
;
Teixeira, Ana Maria
[4]
;
Lira, Fabio Santos
[1]
Total Authors: 4
|
| Affiliation: | [1] Univ Estadual Paulista UNESP, Dept Phys Educ, Postgrad Program Movement Sci, Exercise & Immunometab Res Grp, Presidente Prudente, SP - Brazil
[2] Univ Fed Piaui, Dept Phys Educ, Immunometab Skeletal Muscle & Exercise Res Grp, Teresina - Brazil
[3] Fed Univ Piaui UFPI, Associate Grad Program Hlth Sci, Teresina Pi - Italy
[4] Univ Coimbra, Fac Sport Sci & Phys Educ, Res Ctr Sport & Phys Act UID PTD 04213 2016, Coimbra - Portugal
Total Affiliations: 4
|
| Document type: | Journal article |
| Source: | European Journal of Sport Science; v. 20, n. 1 MAY 2019. |
| Web of Science Citations: | 1 |
| Abstract | |
BDNF is associated with brain health and positively modulated by exercise; however, the influence of physical fitness status on BDNF is incipient. This study investigated the BDNF response after acute-exercise sessions performed at low, moderate, and high intensities and the relationship between physical fitness status and BDNF response. Twenty-eight men, divided according to physical fitness status (50th percentile for VO2max), performed three randomised acute exercise sessions at low (90% of VT1), moderate (midpoint between VT1-VT2), and high (midpoint between VT2-W-max) intensities until exhaustion or for up to 60 min. Lactate and BDNF were determined pre and post-exercises. For BDNF, there were main effects of time (p = 0.003) and interaction (p < 0.001), showing an increase post high-intensity exercise (p < 0.001). Changes in BDNF presented differences between conditions (p < 0.001) with greater increase in high-intensity compared with the others (p = 0.003). For lactate, there were main effects of time (p < 0.001), condition (p < 0.001), and interaction (p < 0.001) with greater concentration in high-intensity. High-intensity exercise exhibited inverse correlation between the changes in BDNF and lactate (r=-0.38, p = 0.044). There was significant correlation between BDNF and VO2max for moderate (r = -0.57, p = 0.002) and a trend for high-intensity condition (r = -0.37, p = 0.050) and when evaluating BDNF according to physical fitness level, it was observed that subjects with lower physical fitness levels had greater increases in BDNF in short-time high-intensity exercise (p = 0.041). In conclusion, short-time high-intensity exercise seems to be more efficient in increasing BDNF concentration, and physical fitness level influences this response, as healthy individuals with lower physical fitness levels were more responsive. (AU) | |
| FAPESP's process: | 14/08003-1 - Involvement of the NF-kB and PPAR-gamma in inflammatory and metabolic response in monocytes of sedentary, physically active and trained individuals |
| Grantee: | Barbara de Moura Mello Antunes |
| Support Opportunities: | Scholarships in Brazil - Doctorate |