New stationary phase for capillary liquid chromatography based on polydimethylsiloxane immobilized onto a Monolithic Silica Support

Author(s)

Pires, Fabiane ^[1] ; Bautista Otalora, Julie Alexandra ^[1] ; Grespan Bottoli, Carla Beatriz ^[1]

Affiliation

^[1] Univ Estadual Campinas, UNICAMP, Inst Chem, Campinas, SP - Brazil

• Document type: Journal article
• Source: SEPARATION SCIENCE PLUS; v. 1, n. 5, p. 343-350, MAY 2018.
• Web of Science Citations: 0

Abstract

A new stationary phase based on polydimethylsiloxane immobilized onto a monolithic silica support was prepared for performing reversed-phase capillary liquid chromatography. Silica monoliths, using tetramethoxysilane as precursor, and hybrid monoliths, using tetramethoxysilane and methyltrimethoxysilane as precursors, were prepared by the sol-gel process. Polydimethylsiloxane was deposited on the monolithic matrix and its immobilization was performed through thermal treatment. Characterization was made by field-emission scanning electron microscopy and by chromatographic evaluation for the separation of six alkylbenzenes. An efficiency of 79 500 plates/m was reached for columns of 200 mu m id, demonstrating that it would be a promising alternative to a reversed-phase column in capillary liquid chromatography. (AU)

• FAPESP's process: 14/21866-9 - Preparation and evaluation of monolithic silica-based modified with poly (dimethyl siloxane) (PDMS) for use in capillary liquid chromatography
• Grantee: Fabiane Pires
• Support Opportunities: Scholarships in Brazil - Master