The rare enterovirus c99 and echovirus 29 strains in Brazil: potential risks associated to silent circulation

Author(s):Show less -

Luchs, Adriana ^[1] ; Leal, Elcio ^[2] ; Tardy, Kaelan ^{[3, 4]} ; de Padua Milagres, Flavio Augusto ^{[5, 6, 7]} ; Komninakis, Shirley Vasconcelos ^{[8, 9]} ; Brustulin, Rafael ^{[5, 6, 7]} ; Rodrigues Teles, Maria da Aparecida ^{[6, 7]} ; Brito Sayao Lobato, Marcia Cristina Alves ^{[6, 7]} ; das Chagas, Rogerio Togisaki ^{[6, 7]} ; Neves dos Santos Abrao, Maria de Fatima ^{[6, 7]} ; de Deus Alves Soares, Cassia Vitoria ^{[6, 7]} ; Deng, Xutao ^{[10, 11]} ; Delwart, Eric ^{[10, 11]} ; Sabino, Ester Cerdeira ^{[3, 4]} ; da Costa, Antonio Charlys ^{[3, 4]}

Affiliation:Show less -

^[1] Adolfo Lutz Inst, Ctr Virol, Nucleo Doencas Enter, Sao Paulo, SP - Brazil

^[2] Univ Fed Para, Inst Ciencias Biol, Belem, Para - Brazil

^[3] Univ Sao Paulo, Inst Med Trop, Sao Paulo, SP - Brazil

^[4] Univ Sao Paulo, Fac Med, LIM 46, Sao Paulo, SP - Brazil

^[5] Univ Fed Tocantins, Palmas, TO - Brazil

^[6] Lab Saude Publ Estado Tocantins, Palmas, TO - Brazil

^[7] Secretaria Saude Tocantins, Palmas, TO - Brazil

^[8] Fac Med ABC, Programa Posgrad Ciencias Saude, Santo Andre, SP - Brazil

^[9] Univ Fed Sao Paulo, Lab Retrovirol, Sao Paulo, SP - Brazil

^[10] Blood Syst Res Inst, San Francisco, CA - USA

^[11] Univ Calif San Francisco, Dept Lab Med, San Francisco, CA 94143 - USA

• Document type: Journal article
• Source: Memórias do Instituto Oswaldo Cruz; v. 114, 2019.
• Web of Science Citations: 0

Abstract

Human enteroviruses (EVs) are associated with a wide spectrum of human diseases. Here we report the complete genome sequences of one EV-C99 strain and one E29 strain obtained from children suffering from acute gastroenteritis, without symptoms of enteroviral syndromes. This is the first report of EV-C99 in South America, and the second E29 genome described worldwide. Continuous surveillance on EVs is vital to provide further understanding of the circulation of new or rare EV serotypes in the country. The present study also highlights the capacity of EVs to remain in silent circulation in populations. (AU)

• FAPESP's process: 17/00021-9 - Viral metagenomics to track, explain and predict the transmission and spatiotemporal spread of Dengue and Chikungunya viruses in Brazil
• Grantee: Antonio Charlys da Costa
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 15/12944-9 - Investigating the evoltution of animal rotavirus strains infecting humans
• Grantee: Adriana Luchs
• Support Opportunities: Regular Research Grants
• FAPESP's process: 16/01735-2 - Viral metagenomics to track, explain and predict the transmission and spatiotemporal spread of Dengue and Chikungunya viruses in Brazil
• Grantee: Ester Cerdeira Sabino
• Support Opportunities: Regular Research Grants