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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Should I stay or should I go: are chlorogenic acids mobilized towards lignin biosynthesis?

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Volpi e Silva, Nathalia [1] ; Mazzafera, Paulo [1, 2] ; Cesarino, Igor [3]
Total Authors: 3
[1] Univ Estadual Campinas, Inst Biol, Dept Plant Biol, Campinas, SP - Brazil
[2] Univ Sao Paulo, Coll Agr Luiz de Queiroz, Dept Crop Sci, Piracicaba, SP - Brazil
[3] Univ Sao Paulo, Inst Biosci, Dept Bot, Rua Matao 277, BR-05508090 Sao Paulo, SP - Brazil
Total Affiliations: 3
Document type: Review article
Source: Phytochemistry; v. 166, OCT 2019.
Web of Science Citations: 7

Chlorogenic acids (CGAs) and the biopolymer lignin are both products of the phenylpropanoid pathway. Whereas CGAs have been reported to play a role during stress responses, lignin is a major component of secondary cell walls, providing physical strength and hydrophobicity to supportive and water-conducting tissues. Because the chemical structure of CGAs largely resembles those of some lignin intermediates and because CGAs can be converted back to hydroxycinnamoyl-CoAs in vitro, CGAs have been considered authentic intermediates of the lignin biosynthetic pathway. However, it is still unclear whether and how the CGA pool can be channeled towards the production of lignin monomers in response to developmental or environmental signals. Comprehensive studies on the catalytic activity of recombinant enzymes together with functional characterizations in planta have been very useful in understanding the potential interdependence between these two metabolic routes. Here we present the current understanding on CGA metabolism and discuss the biochemical and molecular evidence of the metabolic re-routing of CGAs towards lignin. (AU)

FAPESP's process: 14/17831-5 - Chlorogenic acid and its relation with lignin biosynthesis
Grantee:Nathalia Volpi e Silva
Support type: Scholarships in Brazil - Doctorate