Growth performance and intestinal replacement time of C-13 in newly weaned piglets supplemented with nucleotides or glutamic acid

Author(s)

Santos, L. S. ^[1] ; Miassi, G. M. ^[1] ; Tse, M. L. P. ^[1] ; Gomes, L. M. ^[1] ; Berto, P. N. ^[2] ; Denadai, J. C. ^[1] ; Caldara, F. R. ^[3] ; Dalto, D. B. ^[4] ; Berto, D. A. ^[1]

Affiliation

^[1] Sao Paulo State Univ UNESP, Sch Vet Med & Anim Sci, BR-18618970 Botucatu, SP - Brazil

^[2] Univ Sao Paulo, Sch Vet Med & Anim Sci, BR-05508270 Pirassununga - Brazil

^[3] UFGD, Sch Agr, BR-79840000 Dourados, MS - Brazil

^[4] Agr & Agri Food Canada, Sherbrooke Res & Dev Ctr, Sherbrooke, PQ J1M 0C8 - Canada

• Document type: Journal article
• Source: LIVESTOCK SCIENCE; v. 227, p. 160-165, SEP 2019.
• Web of Science Citations: 0

Abstract

Dietary supplementation of nucleotides (NU) and glutamic acid (GA) have been suggested for post-weaned pigs because of their potential role as performance enhancers. During this phase, both additives may become essential for newly weaned piglets acting mainly for energy generation and forming molecular basis that are important for intestinal renewal. Two experiments were conducted to evaluate the effects of dietary NU and GA on growth performance and intestinal replacement time of C-13 in weaned piglets. In both experiments pigs were assigned to treatments in a 2 x 2 factorial arrangement, based on two levels of NU (0 and 0.1%) and two levels of GA (0 and 1%). The energy source of the maternal diet was based on corn (rich in C-13) whereas piglets' post-weaning diets were based on rice (poor in C-13). In the first experiment, 84 piglets were weaned at 21 days of age and growth performance was monitored during three experimental phases (0-15d, 16-27d and 28-35d). In the second experiment, in order to assess the intestinal replacement time of C-13 in weaned piglets, the differences between the natural C-13 abundance in maternal diet and piglets post-weaning diets were used. At day 0 (weaning), three piglets were slaughtered and used as an initial C-13 ratio for duodenum and jejunum. At days 3, 6, 9, 14, 21, 34 and 49, three more piglets by treatment were slaughtered. Exponential regression analysis from each treatment was used to determine the incorporation of C-13 in small intestine tissues between supplemented and control groups (without NU and GA) to determine the C-13 replacement time. In the first study, dietary NU improved G:F (p < 0.05) from day 28-35, whereas dietary GA improved G:F (p < 0.05) from day 0-15, day 28-35 and for the overall experimental period (day 0-35). In the second study, NU supplementation and the interaction of NU x GA improved the replacement time of C-13 in the duodenum mucosa (21.12 +/- 2.14 days and 21.85 +/- 2.13 days, respectively) compared to control (24.95 days). The use of dietary NU and GA during the post-weaning period improves performance but only NU accelerates the replacement time of C-13 on duodenal mucosa during the post-weaning period in pigs. (AU)

• FAPESP's process: 13/18619-7 - NUCLEOTIDES AND GLUTAMIC ACID IN DIETS OF WEANLING PIGLETS
• Grantee: Luan Sousa dos Santos
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 13/25616-4 - Adaptability of weaning piglets receiving diets supplemented with nucleotides and glutamic acid
• Grantee: Dirlei Antonio Berto
• Support Opportunities: Regular Research Grants