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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Anatomic and neuropsychological findings in low-educated cognitively intact elderly from a Brazilian cohort

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Author(s):
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Maria Paula Foss [1] ; Paula Rejane Beserra Diniz [2] ; Daiane Leite da Roza [3] ; Tamar Gefen [4] ; Amanda Cook Maher [5] ; Paulo Formigheri [6] ; Carina T. Spedo [7] ; Carlos Ernesto Garrido Salmon [8] ; Vitor Tumas [9] ; José Geraldo Speciali [10] ; Antônio Carlos Santos [11]
Total Authors: 11
Affiliation:
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[1] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hospital das Clínicas de Ribeirão Preto - Brasil
[2] Universidade Federal de Pernambuco. Center of Telehealth. Department of Clinical Medicine - Brasil
[3] University of São Paulo. Ribeirão Preto Medical School. Department of Neurosciences and Behavioral Sciences - Brasil
[4] Northwestern University. Feinberg School of Medicine. Mesulam Center for Cognitive Neurology and Alzheimer’s Disease Center - Estados Unidos
[5] University of Michigan. Department of Psychiatry. Neuropsychology Division - Estados Unidos
[6] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Program of Internal Medicine - Brasil
[7] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hospital das Clínicas de Ribeirão Preto - Brasil
[8] Universidade de São Paulo. Faculdade de Filosofia. Ciências e Letras de Ribeirão Preto - Brasil
[9] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hospital das Clínicas de Ribeirão Preto - Brasil
[10] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Hospital das Clínicas de Ribeirão Preto - Brasil
[11] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Department Internal Medicine - Brasil
Total Affiliations: 11
Document type: Journal article
Source: Dement. Neuropsychol.; v. 13, n. 4, p. 378-385, 2019-12-09.
Abstract

ABSTRACT In elderly individuals, low educational level may represent a risk factor for the development of dementia and a proxy of cognitive reserve. Objective: This study examined the cognitive and neuroanatomic correlates of high versus low educational levels in cognitively healthy community-dwelling older adults in Brazil. Methods: Fifty-three older adults (mean age: 68±5.3 years) were divided into a “low education” group [LE; 1-4 years of education (N=33)] and “high education” group [HE; >11 years of education (N=20)]. Both groups completed a comprehensive neuropsychological battery and underwent in vivo structural MRI close to the time of testing. Results: Higher educational level increased the chance of having better scores on neuropsychological tests, including verbal and visual delayed recall of information, verbal learning, category fluency, global cognition, and vocabulary. Better scores on these tests were observed in the HE group relative to the LE group. Despite this, there were no group differences between MRI measures. Conclusion: Older adults with higher educational levels showed better scores on neuropsychological measures of cognition, highlighting the need for education-adjusted norms in developing countries. Given the absence of differences in structural anatomy between the groups, these findings appear to be best explained by theories of cognitive reserve. (AU)

FAPESP's process: 18/07581-2 - Mortality in mental disorders with recent onset psychotic manifestations
Grantee:Daiane Leite da Roza
Support Opportunities: Scholarships in Brazil - Post-Doctoral