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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Improving stability of vitamin B12 (Cyanocobalamin) using microencapsulation by spray chilling technique

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Author(s):
Mazzocato, Marcella Chalella [1] ; Thomazini, Marcelo [1] ; Favaro-Trindade, Carmen S. [1]
Total Authors: 3
Affiliation:
[1] Univ Sao Paulo, FZEA, Av Duque de Caxias Norte 225, CP 23, BR-13535900 Pirassununga, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Food Research International; v. 126, DEC 2019.
Web of Science Citations: 1
Abstract

Vitamin-B12 or cyanocobalamin is an essential micronutrient, so it must be supplied by diet. However, vitamin-B12 is found just in foods derived from animals and it is sensitive of many factors. Due to the unrelenting increase of people with deficiency in vitamin-B12 and easy degradation of this vitamin when subjected to adverse conditions, the aim of this research was to produce solid lipid microparticles (SLM) loaded with vitamin-B12 using the spray chilling technique. It was produced 6 SLM (with 0.1 and 1% vitamin and 0, 2.5 and 5% of lecithin) that were analyzed for optical and scanning electron microscopy, size and particles size distribution, water activity, instrumental color, X-ray diffraction, yield and encapsulation efficiency, release profile, besides free and encapsulated vitamin stability for 120 days. It was reported that the SLM presented a spherical shape and smooth surfaces, medium size values varying from 13.28 to 26.99 mu m. The yield and encapsulation efficiency values within the range of 80.7 to 99.7% and from 76.7 to 101.1%, respectively. The encapsulation promoted better protection of vitamin-B12 ( > 91.1% for all formulations after 120 days of storage) when compared to the free one (75.2%). In addition, it was observed a good effect of the presence of soya lecithin in formulations; it promoted a more controlled release of vitamin-B12 in fluids and also shown better stability results. The spray chilling encapsulation technique proved to be a promising alternative, since it protected vitamin-B12 without the necessity of using high temperatures or organic solvents to encapsulate it, besides having a low cost. (AU)

FAPESP's process: 15/19376-6 - Study of the physical-chemical characteristics and solid lipid microparticules stability containing vitamin B12 produced by spray chilling technique
Grantee:Marcella Chalella Mazzocato
Support Opportunities: Scholarships in Brazil - Scientific Initiation