Draft Genome Sequence of a Pseudomonas aeruginosa Sequence Type 3351 Strain Exhibiting High-Level Resistance to Polymyxins in a Pediatric Patient with Cystic Fibrosis in Mexico

Author(s)

Rosales-Reyes, Roberto ^{[1, 2]} ; Esposito, Fernanda ^{[3, 1]} ; Fuga, Bruna ^{[4, 3]} ; Cerdeira, Louise ^[4] ; Gayosso-Vazquez, Catalina ^[2] ; Lezana-Fernandez, Jose L. ^[5] ; Lascurain, Ricardo ^[6] ; Valvano, Miguel A. ^[7] ; Lincopan, Nilton ^{[4, 3, 1]} ; Santos-Preciado, Jose I. ^{[1, 2]}

Affiliation

^[1] Iberoamer Network Combating Antimicrobial Resista, Mexico City, DF - Mexico

^[2] Univ Nacl Autonoma Mexico, Fac Med, Unidad Med Expt, Mexico City, DF - Mexico

^[3] Univ Sao Paulo, Sch Pharmaceut Sci, Dept Clin Anal, Sao Paulo - Brazil

^[4] Univ Sao Paulo, Inst Biomed Sci, Dept Microbiol, Sao Paulo - Brazil

^[5] Hosp Infantil Mexico Dr Federico Gomez, Lab Fisiol Pulm, Mexico City, DF - Mexico

^[6] Univ Nacl Autonoma Mexico, Fac Med, Dept Bioquim, Mexico City, DF - Mexico

^[7] Queens Univ Belfast, Wellcome Wolfson Inst Expt Med, Belfast, Antrim - North Ireland

• Document type: Journal article
• Source: MICROBIOLOGY RESOURCE ANNOUNCEMENTS; v. 9, n. 2 JAN 2020.
• Web of Science Citations: 0

Abstract

Here, we present the draft genome sequence of a Pseudomonas aeruginosa isolate (strain CF16053) belonging to a novel sequence type (ST), ST3351, isolated from a pediatric patient with cystic fibrosis (CF). CF16053 shows high-level resistance to polymyxins associated with mutations in the pmrB gene. Biofilm, pyoverdine, exotoxin A, and type III secretion system (T3SS) genes were identified. (AU)

• FAPESP's process: 19/15578-4 - Virulome and pathogenicity of carbapenem- and polymyxin-resistant priority pathogens
• Grantee: Fernanda Ribeiro dos Santos Esposito
• Support Opportunities: Scholarships in Brazil - Doctorate