Patients with asthma have reduced functional capacity and sedentary behavior

Author(s)

Reimberg, Mariana Mazzuca ^[1] ; Selman Pachi, Jessyca Rodrigues ^[1] ; Scalco, Rebeca Souza ^[1] ; Serra, Andrey Jorge ^{[2, 3]} ; Fernandes, Leandro ^[4] ; Politti, Fabiano ^[1] ; Wandalsen, Gustavo Falbo ^[5] ; Sole, Dirceu ^[5] ; Dal Corso, Simone ^[1] ; Lanza, Fernanda Cordoba ^[1]

Affiliation

^[1] Univ Nove Julho, Programa Posgrad Ciencias Reabil, Sao Paulo, SP - Brazil

^[2] Univ Nove Julho, Programa Posgrad Biofoton Aplicada Ciencia Saude, Sao Paulo, SP - Brazil

^[3] Univ Fed Sao Paulo UNIFESP, Dept Cardiol, Sao Paulo, SP - Brazil

^[4] Univ Fed Sao Paulo UNIFESP, Programa Posgrad Psicobiol, Sao Paulo, SP - Brazil

^[5] Univ Fed Sao Paulo UNIFESP, Dept Pediat, Disciplina Alergia Imunol Clin & Reumatol, Sao Paulo, SP - Brazil

• Document type: Journal article
• Source: Jornal de Pediatria; v. 96, n. 1, p. 53-59, JAN-FEB 2020.
• Web of Science Citations: 0

Abstract

Abstract Objective The modified shuttle test is a field test that avoids the ceiling effect, and there are no reports of a multidimensional assessment concerning physical activity in asthmatic patients. Thus, the aim was to evaluate functional capacity by MST, additionally to perform a multidimensional assessment as physical activity in daily life, muscle strength, and cytokine levels in children and adolescents with asthma, and to correlate these variables. Method This cross-sectional study included volunteers aged between 6 and 18 years who were divided into two groups: asthma group (n = 43) that received regular treatment and control group (n = 24). Functional capacity was evaluated by distance walked during the MST; physical activity in daily life was evaluated using an accelerometer by the number of steps. Quadriceps femoris strength was evaluated by load cell. Results Distance walked was lower for the asthma group (790 m [222 m]) when compared with the control group (950 m [240 m]; p = 0.007); however, the number of steps was similar between the two groups (asthma group: 7743 [3075]; control group: 7181 [3040]; p = 0.41), and both groups were classified as sedentary behavior. There was no difference in muscle strength. Tumor necrosis factor-α differed, but interleukin levels were similar between groups. Quadriceps strength was correlated to distance walked (r = 0.62; p < 0.001) and tumor necrosis factor-α to the number of steps taken (r = −0.54, p = 0.005). Conclusion Children and adolescents undergoing regular asthma treatment showed reduced functional capacity and sedentary behavior. The lower the quadriceps strength, the shorter the distance walked; the higher the tumor necrosis factor-α levels, the lower their daily physical activity levels. (AU)

• FAPESP's process: 16/17553-0 - Relationship between lung function, functional capacity and daily physical activity in asthmatic children and adolescents
• Grantee: Rebeca Souza Scalco
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 14/12040-0 - Physical capacity, peripheral muscle function, inflammation and quality of life in children and adolescents with asthma before and after pulmonary rehabilitation program
• Grantee: Fernanda de Cordoba Lanza
• Support Opportunities: Regular Research Grants