| Full text | |
| Author(s): |
Mejia-Carmona, Karen
[1]
;
da Silva Burato, Juliana Soares
[1]
;
Basolli Borsatto, Joao Victor
[1]
;
de Toffoli, Ana Lucia
[1]
;
Lacas, Fernando Mauro
[1]
Total Authors: 5
|
| Affiliation: | [1] Univ Sao Paulo, Sao Carlos Inst Chem, BR-13560970 Sao Carlos, SP - Brazil
Total Affiliations: 1
|
| Document type: | Review article |
| Source: | TRAC-TRENDS IN ANALYTICAL CHEMISTRY; v. 122, JAN 2020. |
| Web of Science Citations: | 0 |
| Abstract | |
Over the last decade, the use of miniaturized columns in liquid chromatography (LC) has seen intense growth in a wide range of research areas. This report brings an overview of the current developments and applications of miniaturized columns in LC, focused on the type of columns used. Following a short introductory section on some theoretical aspects, the fundamental bases on their design and fabrication, new stationary phases and incorporated materials, performance evaluation/characterization, main advantages, and recent applications of filled capillary and open tubular (OT) capillary columns are introduced and critically discussed. Prospects on the different types of miniaturized columns and their hyphenation with mass spectrometry (MS) reported in the last years are also introduced and discussed. (C) 2019 Elsevier B.V. All rights reserved. (AU) | |
| FAPESP's process: | 17/02147-0 - Single drop chromatography and its coupling to mass spectrometry: instrumental strategies, development of materials, automation and analytical applications |
| Grantee: | Fernando Mauro Lanças |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 15/15462-5 - Employment of graphene as sorbent in miniaturized sample preparation techniques. |
| Grantee: | Bruno Henrique Fumes |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 14/07347-9 - Development of novel materials and devices for miniaturized sample preparation techniques in the area of food safety |
| Grantee: | Fernando Mauro Lanças |
| Support Opportunities: | Regular Research Grants |