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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Genome-wide identification of runs of homozygosity islands in the Gyr breed (Bos indicus)

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Author(s):
Toro Ospina, Alejandra Maria [1] ; da Silva Faria, Ricardo Antonio [1] ; Vercesi Filho, Anibal Eugenio [2] ; dos Santos Goncalves Cyrillo, Joslaine Noely [3] ; Zerlotti Mercadante, Maria Eugenia [3] ; Curi, Rogerio Abdallah [4] ; de Vasconcelos Silva, Josineudson Augusto Ii [4]
Total Authors: 7
Affiliation:
[1] UNESP, Fac Ciencias Agr & Vet, Jaboticabal - Brazil
[2] Inst Zootecnia, Nova Odessa - Brazil
[3] Inst Zootecnia, Sertaozinho - Brazil
[4] UNESP, Fac Med Vet & Zootecnia, Botucatu, SP - Brazil
Total Affiliations: 4
Document type: Journal article
Source: REPRODUCTION IN DOMESTIC ANIMALS; v. 55, n. 3 FEB 2020.
Web of Science Citations: 0
Abstract

Runs of homozygosity (ROH) are contiguous homozygous regions of the genome. These regions can be used to identify genes associated with traits of economic interest, as well as inbreeding levels. The aim of the present study was to analyse the length and distribution of ROH islands in Gyr cattle and to identify genes within these regions. A population of 173 animals selected for beef production and a population of 291 animals selected for dairy production were used. Differences in the number of short ROH (ROH1-2 Mb) were observed between the two populations, while the number of long ROH (ROH>16 Mb) was similar. ROH islands with the highest incidences (>0.50) overlapped in several segments of the genome in the two populations. The genes identified were associated with milk production, growth, reproduction, immune response and resistance traits. Our results contribute to the understanding of how selection can shape the distribution of ROH and ROH islands within the same breed when animals are selected for different purposes such as dairy or beef production. (AU)

FAPESP's process: 15/06686-7 - Population structure evaluation of Gir cattle selected for meat and milk through SNPs arrays
Grantee:Josineudson Augusto Ii de Vasconcelos Silva
Support Opportunities: Regular Research Grants