Population structure evaluation of Gir cattle selected for meat and milk through SNPs arrays

• Grant number: 15/06686-7
• Support Opportunities: Regular Research Grants
• Duration: July 01, 2015 - November 30, 2017
• Field of knowledge: Agronomical Sciences - Animal Husbandry - Genetics and Improvement of Domestic Animals
• Principal Investigator: Josineudson Augusto Ii de Vasconcelos Silva
• Grantee: Josineudson Augusto Ii de Vasconcelos Silva
• Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil
• Associated researchers: Fernando Sebastián Baldi Rey ; Joslaine Noely dos Santos Goncalves Cyrillo ; Maria Eugênia Zerlotti Mercadante ; Rogério Abdallah Curi ; Rusbel Raúl Aspilcueta Borquis

Abstract

The Gyr herds over the years have been selected for the weight growth and milk production, allowing having two different populations. The breeding programs influence the structure of a population as a consequence of a prolonged and unequal genetic contribution of the main ancestors, which associated with the permanence of some bulls for long periods participating in breeding seasons. The genetic markers are used to detect variations between individuals in a specific segment of DNA. Currently, among the molecular markers, emphasis is being given to single nucleotide polymorphism (SNPs), due to the high density of markers around in regions of interest and the possibility of automation of genotyping, assign a low error rate and lower cost. Genetic markers allow measuring the linkage disequilibrium (LD) between a pair of loci through the r2 value considered as LD descriptor and used to obtain the effective population size. Moreover, genetic markers may be used to distinguish populations by identifying sets of markers specific group and to detect recent positive selection of signatures. The aim of this study is to evaluate the genetic structure and genomics, including LD, effective size, and recent positive selection of signature, in two cattle populations Gyr, using high density SNP markers. (AU)

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

TORO OSPINA, ALEJANDRA M.; MAIORANO, AMANDA MARCHI; CURI, ROGERIO A.; PEREIRA, GUILHERME L.; ZERLOTTI-MERCADANTE, MARIA EUGENIA; DOS SANTOS GONCALVES CYRILLO, JOSLAINE NOELY; ASPILCUETA-BORQUIS, RUSBEL R.; SILVA, II, JOSINEUDSON A. DE V.. Linkage disequilibrium and effective population size in Gir cattle selected for yearling weight. REPRODUCTION IN DOMESTIC ANIMALS, OCT 2019. (15/06686-7)

TORO OSPINA, ALEJANDRA MARIA; AGUILAR, IGNACIO; VARGAS DE OLIVEIRA, MATHEUS HENRIQUE; CRUZ DOS SANTOS CORREIA, LUIZ EDUARDO; VERCESI FILHO, ANIBAL EUGENIO; ALBUQUERQUE, LUCIA GALVAO; II DE VASCONCELOS SILVA, JOSINEUDSON AUGUSTO. Assessing the accuracy of imputation in the Gyr breed using different SNP panels. GENOME, v. 64, n. 10, p. 893-899, OCT 2021. (15/06686-7, 17/10630-2)

MAIORANO, AMANDA MARCHI; LOURENCO, DANIELA LINO; TSURUTA, SHOGO; TORO OSPINA, ALEJANDRA MARIA; STAFUZZA, NEDENIA BONVINO; MASUDA, YUTAKA; EUGENIO, ANIBAL; DOS SANTOS GONCALVES CYRILLO, JOSLAINE NOELY; CURI, ROGERIO ABDALLAH; DE VASCONCELOS SILVA, JOSINEUDSON AUGUSTO I. I.. Assessing genetic architecture and signatures of selection of dual purpose Gir cattle populations using genomic information. PLoS One, v. 13, n. 8, AUG 2 2018. (15/06686-7)

TORO OSPINA, ALEJANDRA MARIA; DA SILVA FARIA, RICARDO ANTONIO; VERCESI FILHO, ANIBAL EUGENIO; DOS SANTOS GONCALVES CYRILLO, JOSLAINE NOELY; ZERLOTTI MERCADANTE, MARIA EUGENIA; CURI, ROGERIO ABDALLAH; DE VASCONCELOS SILVA, JOSINEUDSON AUGUSTO II. Genome-wide identification of runs of homozygosity islands in the Gyr breed (Bos indicus). REPRODUCTION IN DOMESTIC ANIMALS, v. 55, n. 3, FEB 2020. (15/06686-7)