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Population structure evaluation of Gir cattle selected for meat and milk through SNPs arrays

Grant number: 15/06686-7
Support type:Regular Research Grants
Duration: July 01, 2015 - November 30, 2017
Field of knowledge:Agronomical Sciences - Animal Husbandry
Principal Investigator:Josineudson Augusto Ii de Vasconcelos Silva
Grantee:Josineudson Augusto Ii de Vasconcelos Silva
Home Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil
Assoc. researchers:Fernando Sebastián Baldi Rey ; Joslaine Noely dos Santos Goncalves Cyrillo ; Maria Eugênia Zerlotti Mercadante ; Rogério Abdallah Curi ; Rusbel Raúl Aspilcueta Borquis


The Gyr herds over the years have been selected for the weight growth and milk production, allowing having two different populations. The breeding programs influence the structure of a population as a consequence of a prolonged and unequal genetic contribution of the main ancestors, which associated with the permanence of some bulls for long periods participating in breeding seasons. The genetic markers are used to detect variations between individuals in a specific segment of DNA. Currently, among the molecular markers, emphasis is being given to single nucleotide polymorphism (SNPs), due to the high density of markers around in regions of interest and the possibility of automation of genotyping, assign a low error rate and lower cost. Genetic markers allow measuring the linkage disequilibrium (LD) between a pair of loci through the r2 value considered as LD descriptor and used to obtain the effective population size. Moreover, genetic markers may be used to distinguish populations by identifying sets of markers specific group and to detect recent positive selection of signatures. The aim of this study is to evaluate the genetic structure and genomics, including LD, effective size, and recent positive selection of signature, in two cattle populations Gyr, using high density SNP markers. (AU)

Articles published in Agência FAPESP Newsletter about the research grant
Genes that could lead to improvement of beef cattle are identified 

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MAIORANO, AMANDA MARCHI; LOURENCO, DANIELA LINO; TSURUTA, SHOGO; TORO OSPINA, ALEJANDRA MARIA; STAFUZZA, NEDENIA BONVINO; MASUDA, YUTAKA; EUGENIO, ANIBAL; DOS SANTOS GONCALVES CYRILLO, JOSLAINE NOELY; CURI, ROGERIO ABDALLAH; DE VASCONCELOS SILVA, JOSINEUDSON AUGUSTO I. I. Assessing genetic architecture and signatures of selection of dual purpose Gir cattle populations using genomic information. PLoS One, v. 13, n. 8 AUG 2 2018. Web of Science Citations: 2.

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