| Full text | |
| Author(s): |
De Almeida, Laiza A.
[1]
;
Marcondes, Thayna H.
[1]
;
Milagre, Cintia D. F.
[1]
;
Milagre, Humberto M. S.
[1]
Total Authors: 4
|
| Affiliation: | [1] Sao Paulo State Univ, UNESP, Inst Chem, BR-14800060 Araraquara, SP - Brazil
Total Affiliations: 1
|
| Document type: | Journal article |
| Source: | CHEMCATCHEM; v. 12, n. 10 APR 2020. |
| Web of Science Citations: | 0 |
| Abstract | |
Herein, we present a robust and eco-friendly dynamic kinetic resolution (DKR) protocol for secondary alcohols using a combined heterogeneous catalytic CAL-B/VOSO4 system at 50 degrees C in the relatively green solvent heptane. This catalytic system is active and chemo- and enantioselective for up to 5 cycles. A set of 13 aromatic and heteroaromatic secondary alcohols were evaluated to determine the substrate scope. The performance of the combined CAL-B/VOSO4 system was improved by employing a low-cost, homemade Teflon tube to compartmentalize the catalysts in one-pot conditions, making this system for up to 8 reaction cycles. (AU) | |
| FAPESP's process: | 14/50249-8 - Green chemistry: sustainable synthetic methods employing benign solvents, safer reagents, and bio-renewable feedstock |
| Grantee: | Arlene Gonçalves Corrêa |
| Support Opportunities: | Research Grants - Research Centers in Engineering Program |