Acute effects of oxytocin in music performance anx... - BV FAPESP
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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Acute effects of oxytocin in music performance anxiety: a crossover, randomized, placebo-controlled trial

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Author(s):
Sabino, Alini D. V. [1] ; Chagas, Marcos Hortes N. [2] ; Osorio, Flavia L. [1, 3]
Total Authors: 3
Affiliation:
[1] Univ Sao Paulo, Med Sch Ribeirao Preto, Ave Bandeirantes 3900, BR-14048900 Ribeirao Preto, SP - Brazil
[2] Univ Fed Sao Carlos, Ctr Biol & Hlth Sci, Sao Carlos - Brazil
[3] CNPq, Natl Inst Sci & Technol INCT TM, Brasilia, DF - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Psychopharmacology; v. 237, n. 6 MAR 2020.
Web of Science Citations: 0
Abstract

Rationale Individuals with music performance anxiety (MPA) present physical, behavioral, and cognitive manifestations of anxiety, in addition to information processing deficits, especially in facial emotion recognition (FER). Objectives To assess the effects of a single dose of intranasal oxytocin (24 IU) on FER in a sample of musicians with high and low MPA (primary outcome), as well as indicators of mood/anxiety and self-assessed performance (secondary outcomes). Methods Crossover, randomized, double-blind, placebo-controlled trial involving 43 male musicians with different levels of MPA. Participants completed a static facial emotion recognition task and self-rated mood and performance scales. Data were analyzed using ANOVA 2 x 0 for crossover trials and the Omnibus test (measure of separability between intervention and carryover effects). Results Only musicians with high MPA treated with oxytocin had a higher accuracy in the recognition of happiness (p < 0.03; d > 0.72). No effects of oxytocin were found on mood indicators or on self-perceived performance, regardless of MPA level. Conclusions The results indicate possible benefits of the acute treatment with oxytocin in MPA, which may improve the management of this common and disabling condition that affects professional musicians. The appropriate perception of positive feedback may increase confidence and feelings of social acceptance, reducing symptoms associated with the condition. The lack of effects on mood/anxiety and cognition may be explained by the context-dependent characteristic of the effects of oxytocin, since the experiment did not represent an actual situation of social threat. (AU)

FAPESP's process: 15/02848-2 - Social and music performance anxiety: acute effects of oxytocin and Ayahuasca in voice, recognition of facial expressions,clinical and cognitive symptoms
Grantee:Flávia de Lima Osório
Support Opportunities: Regular Research Grants