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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

On the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implants

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Author(s):
Correa, D. R. N. [1, 2] ; Rocha, L. A. [1, 3] ; Donato, T. A. G. [1, 3] ; Sousa, K. S. J. [3] ; Grandini, C. R. [1, 3] ; Afonso, C. R. M. [4] ; Doi, H. [5] ; Tsutsumi, Y. [5, 6] ; Hanawa, T. [5]
Total Authors: 9
Affiliation:
[1] IBTN Br Inst Biomat Tribocorros & Nanomed, Brazilian Branch, BR-17033360 Bauru, SP - Brazil
[2] IFSP Fed Inst Educ Sci & Technol, Grp Pesquisa Mat Met Avancados, BR-18095410 Sorocaba, SP - Brazil
[3] Univ Estadual Paulista, Lab Anelasticidade & Biomat, UNESP, BR-17033360 Bauru, SP - Brazil
[4] UFSCar Univ Sao Carlos, Dept Mat Engn, BR-13565905 Sao Carlos, SP - Brazil
[5] Tokyo Med & Dent Univ, Inst Biomat & Bioengn, Chiyoda Ku, Tokyo 1010062 - Japan
[6] Natl Inst Mat Sci, Res Ctr Struct Mat, Tsukuba, Ibaraki 3050047 - Japan
Total Affiliations: 6
Document type: Journal article
Source: JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T; v. 9, n. 2, p. 1241-1250, MAR-APR 2020.
Web of Science Citations: 0
Abstract

This study evaluated the mechanical properties and cytocompatibility of recently developed Ti-15Zr-based alloys with Mo addition for potential use as load-bearing implants. The phase composition and microstructure were changed by the alloying elements, being the beta phase fully retained on the Ti-15Zr-10Mo and Ti-15Zr-15Mo samples. The TEM analysis showed that a small quantity of omega phase was precipitated on the samples with a high amount of Mo. Regarding the mechanical properties, the Ti-15Zr-10Mo sample presented high mechanical strength and large elongation (854 +/- 63 MPa and 18.7 +/- 2.8 %). However, the Ti-15Zr-15Mo sample exhibited better mechanical compatibility, due to its combination of low Young's modulus (75 +/- 1 GPa) and high Vickers microhardness (346 +/- 4 HV). Some dimple-type structures found along the fractured surface confirmed the ductile behavior of these samples. The MTT test indicated non-cytotoxic effects of all samples when in contact with osteoblastic cells (p < 0.05). The wettability values of the samples were adequate for biomedical applications. The mechanical properties of the Ti-15Zr-15Mo sample were better than some commercial metallic biomaterials, which highlights its great potential for use as load-bearing implants. (C) 2019 The Authors. Published by Elsevier B.V. (AU)

FAPESP's process: 10/20440-7 - Effect of substitutional and interstitial elements in the mechanical properties and biocompatibility of Ti-15Zr-xMo alloys
Grantee:Diego Rafael Nespeque Correa
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
FAPESP's process: 15/00851-6 - Biofunctionalization of Ti-15Zr-BASED alloys with molybdenum addition and some surface modifications
Grantee:Diego Rafael Nespeque Correa
Support Opportunities: Scholarships in Brazil - Post-Doctoral