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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Enantioselective S-H Insertion Reactions of alpha-Carbonyl Sulfoxonium Ylides

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Author(s):
Momo, Patricia B. [1] ; Leveille, Alexandria N. [2] ; Farrar, Elliot H. E. [3] ; Grayson, Matthew N. [3] ; Mattson, Anita E. [2] ; Burtoloso, Antonio C. B. [1]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Inst Chem Sao Carlos, BR-13560970 Sao Carlos, SP - Brazil
[2] Worcester Polytech Inst, Dept Chem & Biochem, 100 Inst Rd, Worcester, MA 01609 - USA
[3] Univ Bath, Dept Chem, Claverton Down, Bath BA2 7AY, Avon - England
Total Affiliations: 3
Document type: Journal article
Source: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION; v. 59, n. 36 MAY 2020.
Web of Science Citations: 1
Abstract

The first example of enantioselective S-H insertion reactions of sulfoxonium ylides is reported. Under the influence of thiourea catalysis, excellent levels of enantiocontrol (up to 95 % ee) and yields (up to 97 %) are achieved for 31 examples in S-H insertion reactions of aryl thiols and alpha-carbonyl sulfoxonium ylides. (AU)

FAPESP's process: 13/18009-4 - Molecular design, synthesis and trypanocidal activity of cruzain reversible covalent inhibitors
Grantee:Carlos Alberto Montanari
Support type: Research Projects - Thematic Grants
FAPESP's process: 18/19105-0 - Exploring noncovalent catalysis in enantioselective reactions with Diazoketones and Sulfoxonium Ylides.
Grantee:Patrícia Betoni Momo
Support type: Scholarships abroad - Research Internship - Post-doctor
FAPESP's process: 17/23329-9 - Synthesis of substituted cyclopentanes and long chain polyols from abundant chemical platforms derived from biomass
Grantee:Antonio Carlos Bender Burtoloso
Support type: Regular Research Grants