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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Impact of Oral Care and Antisepsis on the Prevalence of Ventilator-Associated Pneumonia

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Author(s):
Galhardo, Luciana F. [1] ; Ruivo, Gilson F. [2] ; Santos, Fernanda O. [3] ; Ferreira, Tamires T. [3] ; Santos, Juliana [3] ; Leao, Mariella V. P. [4] ; Pallos, Debora [5]
Total Authors: 7
Affiliation:
[1] Univ Taubate, Dept Dent, Taubate, SP - Brazil
[2] Univ Taubate, Dept Med, Taubate, SP - Brazil
[3] Univ Taubate, Taubate, SP - Brazil
[4] Univ Taubate, Basic Biosci Inst, Taubate, SP - Brazil
[5] Univ Santo Amaro UNISA, Santo Amaro, SP - Brazil
Total Affiliations: 5
Document type: Journal article
Source: ORAL HEALTH & PREVENTIVE DENTISTRY; v. 18, n. 2, p. 331-335, MAR-APR 2020.
Web of Science Citations: 0
Abstract

Purpose: This study aimed to evaluate the impact of oral care and use of chlorhexidine gluconate on the prevention of ventilator-associated pneumonia (VAP) in patients admitted to an intensive care unit (ICU). Materials and Methods: An evaluation was performed on 229 patients admitted to ICU in 2012 (before implementation of oral care protocol) and 329 in 2013 (after the protocol). Oral care was based on the removal of secretions from the oral cavity with 0.12% chlorhexidine solution for brushing and sterile gauze for cleaning before a new aspiration. The cases of VAP were evaluated by observing respiratory signs, radiological changes, and culture and laboratory results. The following data were also analysed: gender, length hospital of stay, mechanical ventilation, use of antibiotics and aetiological agent of infection. Results: There was a tendency towards lower risk of development of VAP after application of oral care protocol (odds ratio = 0.64-95% CI: 0.39-1.04). There was also a reduction in the incidence of early pneumonia (up to 72 h of hospitalisation). With regard to the aetiological agent of infections, although Gram-negative bacteria predominated in the two periods studied, there was a decrease in the cases of Staphylococcus aureus infection. Conclusion: Oral care protocol has statistically significantly reduced the risk of developing early VAP in ICU patients, thus demonstrating the importance of multidisciplinary teamwork for hospitalised patients. (AU)

FAPESP's process: 13/08242-3 - Detection of human herpesvirus in human saliva and gingival fluid of patients with chronic renal failure
Grantee:Débora Pallos
Support Opportunities: Regular Research Grants