Combined Aerobic and Resistance Exercises Evokes Longer Reductions on Ambulatory Blood Pressure in Resistant Hypertension: A Randomized Crossover Trial

Author(s)

Pires, Nayara Fraccari ^[1] ; Coelho-Junior, Helio Jose ^{[2, 3]} ; Gambassi, Bruno Bavaresco ^{[2, 4]} ; Cabral de Faria, Ana Paula ^[1] ; Versuti Ritter, Alessandra Mileni ^[1] ; Barboza, Catarina de Andrade ^{[1, 2]} ; Ferreira-Melo, Silvia Elaine ^[1] ; Rodrigues, Bruno ^{[1, 2]} ; Moreno Junior, Heitor ^[1]

Affiliation

^[1] Univ Estadual Campinas, Sch Med Sci, Lab Cardiovasc Pharmacol, UNICAMP, Campinas - Brazil

^[2] Univ Estadual Campinas, Sch Phys Educ FEF, Lab Cardiovasc Invest & Exercise, UNICAMP, Campinas - Brazil

^[3] Univ Cattolica Sacro Cuore, Dept Internal Med & Geriatr, Rome - Italy

^[4] Ceuma Univ, Dept Phys Educ, Sao Luis, Maranhao - Brazil

• Document type: Journal article
• Source: Cardiovascular Therapeutics; v. 2020, AUG 1 2020.
• Web of Science Citations: 0

Abstract

Aim. The present study compared the acute effects of aerobic (AER), resistance (RES), and combined (COM) exercises on blood pressure (BP) levels in people with resistant hypertension (RH) and nonresistant hypertension (NON-RH).Methods. Twenty patients (10 RH and 10 NON-RH) were recruited and randomly performed three exercise sessions and a control session. Ambulatory BP was monitored over 24 hours after each experimental session.Results. Significant reductions on ambulatory BP were found in people with RH after AER, RES, and COM sessions. Notably, ambulatory BP was reduced during awake-time and night-time periods after COM. On the other hand, the effects of AER were more prominent during awake periods, while RES caused greater reductions during the night-time period. In NON-RH, only RES acutely reduced systolic BP, while diastolic BP was reduced after all exercise sessions. However, the longest postexercise ambulatory hypotension was observed after AER (similar to 11 h) in comparison to RES (similar to 8 h) and COM (similar to 4 h) exercises.Conclusion. Findings of the present study indicate that AER, RES, and COM exercises elicit systolic and diastolic postexercise ambulatory hypotension in RH patients. Notably, longer hypotension periods were observed after COM exercise. In addition, NON-RH and RH people showed different changes on BP after exercise sessions, suggesting that postexercise hypotension is influenced by the pathophysiological bases of hypertension. (AU)

• FAPESP's process: 17/21320-4 - Effects of transcranial direct current stimulation (tDCS) on breathing variability and post-exercise hypotension in resistant hypertensive subjects
• Grantee: Bruno Rodrigues
• Support Opportunities: Regular Research Grants
• FAPESP's process: 16/18104-5 - Sympatholytic effects of transcranial direct current stimulation (tDCS) on blood pressure levels in resistant hypertensive subjects - A novel therapeutic approach
• Grantee: Heitor Moreno Junior
• Support Opportunities: Regular Research Grants