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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Tissue reaction and anti-biofilm action of new biomaterial composed of latex from Hancornia speciosa Gomes and silver nanoparticles

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Author(s):
JÉSSICA M. BONETE [1] ; GUILHERME D. SILVA [2] ; ÉDER J. GUIDELLI [3] ; PABLO J. GONÇALVES [4] ; LUCIANE M. ALMEIDA [5] ; OSWALDO BAFFA [6] ; ANGELA KINOSHITA
Total Authors: 7
Affiliation:
[1] Universidade do Sagrado Coração/USC - Brasil
[2] Universidade do Sagrado Coração/USC - Brasil
[3] Universidade de São Paulo/FFCLRP. Departamento de Física - Brasil
[4] Universidade Federal de Goiás/UFG. Instituto Física - Brasil
[5] Universidade Estadual de Goiás/UEG - Brasil
[6] Universidade de São Paulo/FFCLRP. Departamento de Física - Brasil
Total Affiliations: 7
Document type: Journal article
Source: Anais da Academia Brasileira de Ciências; v. 92, n. 4 2020-11-16.
Abstract

Abstract In this work, the natural latex extracted from Harconia speciosa was incorporated with silver nanoparticles (AgNP) to compose a functional biomaterial associating the intrinsic angiogenic activity of the latex and the antimicrobial activity of AgNP. Tissue reaction after subcutaneous implantation in dorsum of rats of membranes without AgNP and with 0.05%, 0.4% AgNP was compared at 3, 7 and 25 days. No statistically significant difference in the tissue response of the different biomaterials was observed, indicating that AgNP did not interfere with the inflammatory reaction (p > 0.05) or with the angiogenic activity of latex. Biomembranes were also tested against bacterial biofilm formation by Staphylococcus aureus and the antimicrobial activity of the new biomaterial can be found with bacteria crenation (0.05% AgNP) and no biofilm deposition (0.4% AgNP). Therefore, this biomaterial has interesting properties for the tissue repair process and may be feasible for future applications as dressing. (AU)

FAPESP's process: 13/07699-0 - Research, Innovation and Dissemination Center for Neuromathematics - NeuroMat
Grantee:Oswaldo Baffa Filho
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC
FAPESP's process: 16/06399-0 - Development and tissue reaction of a new latex composite Hancornia speciosa Gomes and silver nanoparticles
Grantee:Jéssica Mariana Bonete
Support Opportunities: Scholarships in Brazil - Scientific Initiation