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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Uterine vascular resistance and other maternal factors associated with the risk of developing hypertension during pregnancy

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Author(s):
L.A.B. Martins [1] ; E.C.A. Veiga [2] ; C.C.C. Ribeiro [3] ; V.M.F. Simões [4] ; V.C. Cardoso [5] ; H. Bettiol [6] ; M.A. Barbieri [7] ; R.C. Cavalli [8]
Total Authors: 8
Affiliation:
[1] Faculdade de Ciências da Saúde de Barretos Dr. Paulo Prata - Brasil
[2] Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo - Brasil
[3] Departamento de Odontologia II, Universidade Federal do Maranhão - Brasil
[4] Departamento de Saúde Pública, Universidade Federal do Maranhão - Brasil
[5] Departamento de Puericultura e Pediatria, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo - Brasil
[6] Departamento de Puericultura e Pediatria, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo - Brasil
[7] Departamento de Puericultura e Pediatria, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo - Brasil
[8] Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo - Brasil
Total Affiliations: 8
Document type: Journal article
Source: Brazilian Journal of Medical and Biological Research; v. 54, n. 1 2020-11-18.
Abstract

Gestational hypertension and pre-eclampsia are important causes of perinatal morbidity. The objective of the present study was to determine the increase in relative risk for developing hypertensive disorders of pregnancy based on the evaluation of pregnant women between 20 and 25 weeks of gestation, and to correlate the findings at this period with the outcome of pregnancy. We conducted a prospective cohort study, with a convenience sample of 1417 patients evaluated at this gestational age, of which 1306 were contacted at childbirth. We detected an increased relative risk of 2.69 (95%CI: 1.86 to 3.89) associated with pulsatility index of the uterine arteries, a 2.8 increase (95%CI: 1.58 to 5.03) in relative risk attributed to maternal age above 35 years, a 1.68 increase (95%CI: 1.17 to 2.40) attributed to parity greater than or equal to 3, and a 5.35 increase (95%CI: 4.18 to 6.85) attributed to chronic hypertension and obesity, with a progressive increase in relative risk according to the degree of overweight, i.e., grades 1, 2, 3, and morbid obesity (2.58, 3.06, 5.84, and 7.28, respectively). (AU)

FAPESP's process: 08/53593-0 - Etiological factors of preterm birth and consequences of perinatal factors in child health: birth cohorts in two Brazilian cities (BRISA project)
Grantee:Marco Antonio Barbieri
Support Opportunities: Research Projects - Thematic Grants