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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Coated Surface on Ti-30Ta Alloy for Biomedical Application: Mechanical and in-vitro Characterization

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Author(s):
Patricia Capellato [1] ; Samira E. A. Camargo [2] ; Gilbert Silva [3] ; Daniela Sachs [4] ; Filipe Bueno Vilela [5] ; Cecilia A. de C. Zavaglia [6] ; Ketul C. Popat [7] ; Ana P.R. Alves Claro [8]
Total Authors: 8
Affiliation:
[1] Universidade Federal de Itajubá. Instituto de Física e Química - Brasil
[2] University of Florida. College of Dentistry. Restorative Dental Sciences - Estados Unidos
[3] Universidade Federal de Itajubá. Instituto de Engenharia Mecânica - Brasil
[4] Universidade Federal de Itajubá. Instituto de Física e Química - Brasil
[5] Universidade Federal de Itajubá. Instituto de Física e Química - Brasil
[6] Universidade Estadual de Campinas. Faculdade de Engenharia Mecânica - Brasil
[7] Colorado State University. Department of mechanical Engineering. School of Biomedical Engineering - Estados Unidos
[8] Universidade Estadual Paulista. Faculdade de Engenharia. Campus Guaratinguetá - Brasil
Total Affiliations: 8
Document type: Journal article
Source: MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS; v. 23, n. 6 2020-11-27.
Abstract

Several studies have been carried out to develop new materials for biomedical applications. Material surfaces that present biomimetic morphology like nanotubes or nanofibers that provides nanoscale architectures have been shown to alter cell/biomaterial interactions. The coated surface biomaterial with biocompatible polymers and nanotubes of TiO2 is an alternative to improve osseointegration. The anodization process was performed to obtain nanotubes of TiO2 covering the Ti-30Ta alloy surface and the electrospinning process has been used for producing polymer fibers. Characterization techniques such as scanning electron microscopy (SEM - FEG), X-ray diffraction analysis (X-rays), thermogravimetric analysis (TGA), Differential Scanning Calorimetry (DSC) and contact angle were used for samples analyses. Adult human adipose-derived stem cells (ADSCs) were used to investigate the cellular response and S. aureus antimicrobial activity on these coated surfaces. The results indicated that both surface modification treatment showed a favorable micro-environment for cells growth and proliferation such as adhesion, viability and morphology which is a desire property for an implant. In addition, the antimicrobial activity study presented both materials with similar growth of S. aureus. So, it can conclude nanotubes and nanofibers can be used at biomedical field and both present similar cell evaluation and antimicrobial activity results. (AU)

FAPESP's process: 14/14533-3 - Evaluation of PCL electrospun fibers on the Ti-30Ta alloy surface after TiO2 nanotubes growth
Grantee:Patricia Capellato
Support Opportunities: Scholarships in Brazil - Post-Doctoral