Amount of Dentifrice and Fluoride Concentration Influence Salivary Fluoride Concentrations and Fluoride Intake by Toddlers

Author(s)

Sampaio, Caio ^[1] ; Delbem, Alberto Carlos Botazzo ^[1] ; Paiva, Mayra Frasson ^[1] ; Zen, Igor ^[1] ; Danelon, Marcelle ^[1] ; Cunha, Robson Frederico ^[1] ; Pessan, Juliano Pelim ^[1]

Affiliation

^[1] Sao Paulo State Univ UNESP, Sch Dent, Dept Prevent & Restorat Dent, Rua Jose Bonifacio 1193, BR-16015050 Aracatuba, SP - Brazil

• Document type: Journal article
• Source: Caries Research; v. 54, n. 3, p. 234-241, OCT 2020.
• Web of Science Citations: 0

Abstract

The present study evaluated fluoride (F) concentrations in saliva of toddlers after brushing with dentifrices containing different F concentrations, applied in different quantities, and estimated F intake from toothbrushing. The study comprised a double-blind, crossover protocol, in which toddlers (n= 18, 2-3 years old) were randomly assigned into six groups, according to possible combinations of dentifrices (0/550/1,100 ppm F, as NaF) and amounts (rice grain, pea size, and transverse technique). Volunteers used a F-free dentifrice during 1 week. On the 7th day, saliva samples were collected before (baseline), and at 5/15/30/60 min after toothbrushing. All dentifrice expectorated after brushing was collected. F concentrations (saliva and expectorate) were determined with an ion-specific electrode. Data were submitted to ANOVA or Kruskal-Wallis test, followed by Fisher's LSD or Student-Newman-Keuls' tests (p<0.05). Brushing with 550 ppm F dentifrice (pea size or transversal technique) increased the area under the curve (AUC) at similar levels compared to 1,100 ppm F (rice grain). The highest AUC and salivary F at 5 min after brushing were achieved by 1,100 ppm F (pea size), followed by 550 ppm F (transversal technique). Regarding F intake, the highest values were observed for 550 ppm F (transversal technique), followed by 1,100 ppm F (pea size). It is possible to conclude that the amount of dentifrice and F concentration in the product significantly affected both salivary F concentrations and F intake during toothbrushing. (AU)

• FAPESP's process: 17/07424-1 - Influence of the amount of dentifrice and fluoride concentration on intraoral fluoride uptake and on fluoride intake by children: in vivo study
• Grantee: Caio Sampaio
• Support Opportunities: Scholarships in Brazil - Master