Fatal Outcome of Ilheus Virus in the Cerebrospinal Fluid of a Patient Diagnosed with Encephalitis

Author(s)

Milhim, Bruno H. G. A. ^[1] ; Estofolete, Cassia F. ^[1] ; da Rocha, Leonardo C. ^[1] ; Liso, Elisabete ^[2] ; Brienze, Vania M. S. ^[2] ; Vasilakis, Nikos ^{[3, 4, 5, 6]} ; Terzian, Ana C. B. ^{[1, 7]} ; Nogueira, Mauricio L. ^[1]

Affiliation

^[1] Fac Med Sao Jose do Rio Preto FAMERP, Lab Pesquisas Virol LPV, Ave Brigadeiro Faria Lima 5544, BR-15090000 Sao Jose Do Rio Preto - Brazil

^[2] Hosp Base, Ave Brigadeiro Faria Lima 5544, BR-15090000 Sao Jose Do Rio Preto, SP - Brazil

^[3] Univ Texas Med Branch, Dept Pathol, 301 Univ Blvd, Galveston, TX 77555 - USA

^[4] Univ Texas Med Branch, Ctr Biodef & Emerging Infect Dis, 301 Univ Blvd, Galveston, TX 77555 - USA

^[5] Univ Texas Med Branch, Ctr Trop Dis, 301 Univ Blvd, Galveston, TX 77555 - USA

^[6] Univ Texas Med Branch, Inst Human Infect & Immun, 301 Univ Blvd, Galveston, TX 77555 - USA

^[7] Inst Rene Rachou Fiocruz Minas, Lab Immunol Cellular & Mol Biol, BR-30190002 Barro Preto, Bh Mg - Brazil

• Document type: Journal article
• Source: Viruses-Basel; v. 12, n. 9 SEP 2020.
• Web of Science Citations: 0

Abstract

Ilheus virus is an arbovirus with the potential for central nervous system involvement. Accurate diagnosis is a challenge due to similar clinical symptoms and serologic cross-reactivity with other flaviviruses. Here, we describe the first documented case of a fatal outcome following the identification of Ilheus virus in the cerebrospinal fluid (CSF) of a patient with cerebral encephalitis in Brazil. (AU)

• FAPESP's process: 13/21719-3 - Epidemiological study of dengue (serotypes1-4) in a cohort of São José do Rio Preto, São Paulo, Brazil, during 2014-2018
• Grantee: Maurício Lacerda Nogueira
• Support Opportunities: Research Projects - Thematic Grants