| Full text | |
| Author(s): |
Soares-Yoshikawa, Aline Laignier
[1]
;
Varanda, Thais
[1]
;
Iwamoto, Alexsandra Shizue
[1]
;
Kantovitz, Kamila Rosamilia
[1, 2]
;
Puppin-Rontani, Regina Maria
[1]
;
Pascon, Fernanda Miori
[1]
Total Authors: 6
|
| Affiliation: | [1] State Univ Campinas UNICAMP, Piracicaba Dent Sch, Dept Hlth Sci & Pediat Dent, Piracicaba, SP - Brazil
[2] Fac Sao Leopoldo Mand, Dental Mat Area, Campinas, SP - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | MICROSCOPY RESEARCH AND TECHNIQUE; v. 84, n. 5 DEC 2020. |
| Web of Science Citations: | 0 |
| Abstract | |
This study evaluated the fluoride (F) release and remineralizing potential of varnishes containing sodium fluoride (5% NaF), 5% NaF with CPP-ACP and 5% NaF with TCP in early caries lesions in primary teeth. To determine the F release at 1, 4, 6, 24, 72, and 168 hr, strips were covered with the varnishes and immersed in purified water (n = 7). The varnishes and purified water (negative control) were applied on enamel blocks with early caries lesions (n = 16). Enamel blocks were stored in artificial saliva and submitted to a pH-cycling. The area of enamel hardness loss (Delta S) was analyzed by microhardness, lesion depth by polarized light microscopy (PLM) and the chemical analysis by Energy-dispersive X-ray spectroscopy. Data were submitted to Shapiro-Wilk, two-way and one-way ANOVA, Tukey and paired t-tests (alpha = 5%). All varnishes released F, but 5% NaF with CPP-ACP had the highest release at 4, 6, 24, and 72 hr (p < .05) followed by 5% NaF with TCP and 5% NaF. No significant difference in Delta S was observed among varnishes (5% NaF = 4,098.4 +/- 1,407.9; 5% NaF with CPP-ACP = 4,164.0 +/- 1,019.3; 5% NaF with TCP = 4,183.2 +/- 1,527.2; p = .999), but all of them differed from the negative control group (6,757.8 +/- 2,274.7; p < .001). Lesion depth was lower in varnishes groups compared to negative control (% reduction: 5% NaF = 41.8%, 5% NaF with CPP-ACP = 38.8%, and 5% NaF with TCP = 36.3%; p < .001). Similar Ca, P, and Ca/P ratio percentages among groups and F was not detected after the treatments. All fluoride varnishes showed potential to enhance remineralization of early caries lesions in primary teeth. (AU) | |
| FAPESP's process: | 12/03036-3 - Qualitative and quantitative evaluation of the remineralizing potential of different fluoride varnishes in white spot lesions produced in vitro in primary teeth |
| Grantee: | Thais Varanda |
| Support Opportunities: | Scholarships in Brazil - Master |