Advanced search
Start date
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Overcoming matrix effects in the analysis of pyrethroids in honey by a fully automated direct immersion solid-phase microextraction method using a matrix-compatible fiber

Full text
Belinato, Joao Raul [1, 2, 3] ; Grandy, Jonathan J. [3] ; Khaled, Abir [3] ; Suarez, Paola Alejandra Ortiz [3] ; Pawliszyn, Janusz [3]
Total Authors: 5
[1] Univ Estadual Campinas, Inst Chem, BR-13083970 Campinas, SP - Brazil
[2] Natl Inst Sci & Technol Bioanal INCTBio, Campinas, SP - Brazil
[3] Univ Waterloo, Dept Chem, 200 Univ Ave West, Waterloo, ON N2L 3G1 - Canada
Total Affiliations: 3
Document type: Journal article
Source: Food Chemistry; v. 340, MAR 15 2021.
Web of Science Citations: 0

Pyrethroids insecticides may constitute a major hazard to honeybees, leading to colony collapse disorder. However, the determination of pyrethroids in honey has remained a challenging undertaking for analysts to date due to the high complexity of this matrix as well as the MRLs. This paper presents a fully automated method to overcome matrix influences using matrix-compatible overcoated SPME fiber for quantitative analysis of pyrethroids in diluted honey by GC-MS. The developed method was optimized using a multivariate approach providing LOQ values much lower than the stablished MRL (0.10-10 ng/g), while granting satisfactory linearity (R-2 > 0.998) in a wide linear range of 0.1-2000 ng/g, repeatability with RSDs < 10%, reproducibility RSDs < 20%, and accuracy ranging from 75 to 118% and from 82 to 120 % for inter-day and intra-day assays, respectively by using five replicates. The method herein proposed overcomes challenges presented by complex matrices while minimizing sample handling and the overall complexity of the procedure. (AU)

FAPESP's process: 18/25729-7 - High throughput biocompatible SPME coatings for metabolomic analyses
Grantee:Joao Raul Belinato de Souza
Support type: Scholarships abroad - Research Internship - Doctorate
FAPESP's process: 16/20547-2 - Characterization of the metabolome of anti-phytopatogen microorganisms by Multidimensional Gas Chromatography and Simple / Tandem Mass Spectrometry (GC×GC-QMS and GC×GC-MS/MS)
Grantee:Joao Raul Belinato de Souza
Support type: Scholarships in Brazil - Doctorate