Bacterial Nanocellulose in Dentistry: Perspectives and Challenges

Author(s)

de Oliveira Barud, Helida Gomes ^[1] ; da Silva, Robson Rosa ^[2] ; Borges, Marco Antonio Costa ^[3] ; Castro, Guillermo Raul ^{[4, 5]} ; Ribeiro, Sidney Jose Lima ^[6] ; da Silva Barud, Hernane ^[3]

Affiliation

^[1] BioSmart Nanotechnol, LTDA, Av Jorge Fernandes Sao Mattos 311, BR-14808162 Araraquara, SP - Brazil

^[2] Chalmers Univ Technol, Dept Chem & Chem Engn, S-41296 Gothenburg - Sweden

^[3] Univ Araraquara, Lab Biopolimeros & Biomat, UNIARA, Rua Carlos Gomes 1217 Ctr, BR-1217CENT Araraquara, SP 14801340 - Brazil

^[4] Univ Nacl La Plata, UNLP Dept Quim, RA-1900 Buenos Aires, DF - Argentina

^[5] Max Planck Lab Struct Biol Chem & Mol Biophys Ros, UNR MPIbpC, S2002LRK, Rosario - Argentina

^[6] Sao Paulo State Univ, UNESP, Inst Chem, Rua Prof Francisco Degni, BR-14800060 Araraquara, SP - Brazil

• Document type: Review article
• Source: Molecules; v. 26, n. 1 JAN 2021.
• Web of Science Citations: 0

Abstract

Bacterial cellulose (BC) is a natural polymer that has fascinating attributes, such as biocompatibility, low cost, and ease of processing, being considered a very interesting biomaterial due to its options for moldability and combination. Thus, BC-based compounds (for example, BC/collagen, BC/gelatin, BC/fibroin, BC/chitosan, etc.) have improved properties and/or functionality, allowing for various biomedical applications, such as artificial blood vessels and microvessels, artificial skin, and wounds dressing among others. Despite the wide applicability in biomedicine and tissue engineering, there is a lack of updated scientific reports on applications related to dentistry, since BC has great potential for this. It has been used mainly in the regeneration of periodontal tissue, surgical dressings, intraoral wounds, and also in the regeneration of pulp tissue. This review describes the properties and advantages of some BC studies focused on dental and oral applications, including the design of implants, scaffolds, and wound-dressing materials, as well as carriers for drug delivery in dentistry. Aligned to the current trends and biotechnology evolutions, BC-based nanocomposites offer a great field to be explored and other novel features can be expected in relation to oral and bone tissue repair in the near future. (AU)

• FAPESP's process: 13/07793-6 - CEPIV - Center for Teaching, Research and Innovation in Glass
• Grantee: Edgar Dutra Zanotto
• Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC
• FAPESP's process: 18/25512-8 - Biocelulose-based Cell Culture Platform
• Grantee: Hernane da Silva Barud
• Support Opportunities: Regular Research Grants