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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Organochlorine pesticide analysis in milk by gas-diffusion microextraction with gas chromatography-electron capture detection and confirmation by mass spectrometry

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Author(s):
Lobato, Alnilan [1] ; Fernandes, Virginia Cruz [2] ; Pacheco, Joao G. [2] ; Delerue-Matos, Cristina [2] ; Goncalves, Luis Moreira [1]
Total Authors: 5
Affiliation:
[1] Univ Sao Paulo, Dept Quim Fundamental, Inst Quim, Sao Paulo, SP - Brazil
[2] Inst Politecn Porto, Inst Super Engn Porto ISEP, REQUIMTE LAQV, Porto - Portugal
Total Affiliations: 2
Document type: Journal article
Source: Journal of Chromatography A; v. 1636, JAN 11 2021.
Web of Science Citations: 4
Abstract

Organochlorine pesticides (OCPs) are synthetic compounds less used nowadays due to their toxicity combined with slow degradation which leads to accumulation in the environment. Gas-diffusion microextraction (GDME) was employed prior to gas chromatography with electron capture detection (GC-ECD) and mass spectrometry (GC-MS). For the first time, the low-cost, eco-friendly GDME system was used to extract the OCPs directly from milk samples and associated with GC-ECD. Parameters that affect GDME's performance (extract volume, extraction time, and temperature) were optimized. The calibration curves of all OCPs (alpha- and beta-hexachlorocyclohexane, lindane, hexachlorobenzene, p,p'-DDE, aldrin, dieldrin, and alpha-endosulfan) had coefficients of determination (r(2)) ranging from 0.991 to 0.995, and limits of detection (LODs) values ranging from 3.7 to 4.8 mu g L-1. This method also provided satisfactory values for precision with relative standard deviations (RSDs) lower than 10% and recoveries above 90%. As a proof-of-concept, several commercial milk samples were analyzed, aldrin was found in one of them but below the maximum residue limits. (C) 2020 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 18/14425-7 - A new synergetic path for gas-diffusion microextraction (GDME) making use of molecular imprinted polymers (MIPs)
Grantee:Luís Francisco Moreira Gonçalves
Support Opportunities: Research Grants - Young Investigators Grants
FAPESP's process: 19/11214-8 - Application of capillary electrophoresis for the determination of aldehydes after extraction by GDME-MIPs
Grantee:Alnilan Cristina Barros Lobato
Support Opportunities: Scholarships in Brazil - Master