A ubiquitous tire rubber-derived chemical induces acute mortality in coho salmon

Author(s):Show less -

Tian, Zhenyu ^{[1, 2]} ; Zhao, Haoqi ^[3] ; Peter, Katherine T. ^{[1, 2]} ; Gonzalez, Melissa ^{[1, 2]} ; Wetzel, Jill ^[4] ; Wu, Christopher ^{[1, 2]} ; Hu, Ximin ^[3] ; Prat, Jasmine ^[4] ; Mudrock, Emma ^[4] ; Hettinger, Rachel ^{[1, 2]} ; Cortina, Allan E. ^{[1, 2]} ; Biswas, Rajshree Ghosh ^[5] ; Kock, Flavio Vinicius Crizostomo ^[5] ; Soong, Ronald ^[5] ; Jenne, Amy ^[5] ; Du, Bowen ^[6] ; Hou, Fan ^[3] ; He, Huan ^[3] ; Lundeen, Rachel ^{[1, 2]} ; Gilbreath, Alicia ^[7] ; Sutton, Rebecca ^[7] ; Scholz, Nathaniel L. ^[8] ; Davis, Jay W. ^[9] ; Dodd, Michael C. ^[3] ; Simpson, Andre ^[5] ; McIntyre, Jenifer K. ^[4] ; Kolodziej, Edward P. ^{[3, 1, 2]}

Affiliation

^[1] Ctr Urban Waters, Tacoma, WA 98421 - USA

^[2] Univ Washington Tacoma, Interdisciplinary Arts & Sci, Tacoma, WA 98421 - USA

^[3] Univ Washington, Dept Civil & Environm Engn, Seattle, WA 98195 - USA

^[4] Washington State Univ, Sch Environm, Puyallup, WA 98371 - USA

^[5] Univ Toronto, Dept Chem, Scarborough Campus, 1265 Mil Trail, Toronto, ON M1C 1A4 - Canada

^[6] Southern Calif Coastal Water Res Project, Costa Mesa, CA 92626 - USA

^[7] San Francisco Estuary Inst, 4911 Cent Ave, Richmond, CA 94804 - USA

^[8] NOAA, Environm & Fisheries Sci Div, Northwest Fisheries Sci Ctr, Natl Marine Fisheries Serv, Seattle, WA 98112 - USA

^[9] US Fish & Wildlife Serv, Washington Fish & Wildlife Off, Lacey, WA 98503 - USA

• Document type: Journal article
• Source: Science; v. 371, n. 6525, p. 185-189, JAN 8 2021.
• Web of Science Citations: 49

Abstract

In U.S. Pacific Northwest coho salmon (Oncorhynchus kisutch), stormwater exposure annually causes unexplained acute mortality when adult salmon migrate to urban creeks to reproduce. By investigating this phenomenon, we identified a highly toxic quinone transformation product of N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD), a globally ubiquitous tire rubber antioxidant. Retrospective analysis of representative roadway runoff and stormwater-affected creeks of the U.S. West Coast indicated widespread occurrence of 6PPD-quinone (<0.3 to 19 micrograms per liter) at toxic concentrations (median lethal concentration of 0.8 +/- 0.16 micrograms per liter). These results reveal unanticipated risks of 6PPD antioxidants to an aquatic species and imply toxicological relevance for dissipated tire rubber residues. (AU)

• FAPESP's process: 19/14770-9 - Study of binding interactions between agrochemicals towards organic matters and small living organisms by advanced NMR approaches
• Grantee: Flavio Vinicius Crizostomo Kock
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• FAPESP's process: 18/16040-5 - Biorational control of Pest-Insect
• Grantee: Flavio Vinicius Crizostomo Kock
• Support Opportunities: Scholarships in Brazil - Post-Doctoral