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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Evaluation of acute cardiorespiratory and hemodynamic changes in perioperative intravenous antimicrobial applications in cats

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Author(s):
P.R.S. Gomide [1] ; R.C. Costa [2] ; L.G. Faria [3] ; J.T. Brondani ; A.P. Gering [5] ; A. Escobar [6] ; B.P. Santarosa [7] ; B.W. Minto [8]
Total Authors: 8
Affiliation:
[1] Universidade Estadual Paulista. Faculdade de Ciências Agrárias e Veterinárias - Brasil
[2] Universidade Estadual Paulista. Faculdade de Ciências Agrárias e Veterinárias - Brasil
[3] Universidade Estadual Paulista. Faculdade de Ciências Agrárias e Veterinárias - Brasil
[5] Universidade Estadual Paulista. Faculdade de Ciências Agrárias e Veterinárias - Brasil
[6] Universidade Estadual Paulista. Faculdade de Ciências Agrárias e Veterinárias - Brasil
[7] Universidade Federal dos Vales do Jequitinhonha e Mucuri. Instituto de Ciências Agrárias - Brasil
[8] Universidade Estadual Paulista. Faculdade de Ciências Agrárias e Veterinárias - Brasil
Total Affiliations: 8
Document type: Journal article
Source: Arquivo Brasileiro de Medicina Veterinária e Zootecnia; v. 73, n. 1, p. 91-98, 2021-02-15.
Abstract

ABSTRACT The metabolic peculiarities of felines favor an intoxication. Fifty healthy female cats were divided into five groups: PG (placebo group), G2 (cefazolin), G3 (ceftriaxone), G4 (enrofloxacin) and G5 (ampicillin) were used. The parameters evaluated were: total expired carbon dioxide (ETCO2), oxygen saturation in hemoglobin (SpO2), heart rate (HR), respiratory rate (RR), body temperature (BT), systolic, mean and diastolic blood pressure (SBP, mBP and DBP) by invasive method, at T0, 5 (T5), 10 (T10), 15 (T15), 20 (T20), 25 (T25) and 30 (T30) minutes after administration of the treatments. HR presented reduction in G2 compared to PG at all times, except T20, and in G4, T25 and T30 were lower than the T0 values (P<0.05). BT showed increase in the G3 at T0 and T5 and all groups showed reduction in the values of BT relative to T0 (P<0.05). ETCO2 increased in G2 and G5 at all times compared to PG (P<0.05) and there were no differences among the times within each group. It was concluded that ceftriaxone is safer for the prophylactic antimicrobial use in cats, however the other antimicrobials are also indicated, because all the parameters, in all groups, basically did not change over the study and when this occurs it remains in reference interval. (AU)

FAPESP's process: 13/18096-4 - Evaluation of cardiorespiratory changes of the use of perioperative antibiotics intravenously in cats (Felis catus, L. 1766)
Grantee:Rodrigo Casarin Costa
Support Opportunities: Scholarships in Brazil - Scientific Initiation