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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Depression and frailty in older adults: A population-based cohort study

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Author(s):
Figueiredo Da Mata, Fabiana Araujo [1] ; Forte Gomes, Marilia Miranda [2] ; Ferreira Santos, Jair Licio [3] ; de Oliveira Duarte, Yeda Aparecida [4] ; Pereira, Mauricio Gomes [1]
Total Authors: 5
Affiliation:
[1] Univ Brasilia, Fac Med, Brasilia, DF - Brazil
[2] Univ Brasilia, Fac Gama, Brasilia, DF - Brazil
[3] Univ Sao Paulo, Dept Social Med, Sao Paulo, SP - Brazil
[4] Univ Sao Paulo, Sch Nursing, Dept Med Surg Nursing, Sao Paulo, SP - Brazil
Total Affiliations: 4
Document type: Journal article
Source: PLoS One; v. 16, n. 3 MAR 4 2021.
Web of Science Citations: 0
Abstract

Background Studies have shown an association between depression and frailty, even though the literature has not reached a consensus regarding how these syndromes interact. Although prospective cohort studies on this topic are still scarce, they could contribute to understanding this relationship. We aimed to observe whether depressive symptoms are risk factors for the onset of frailty among older adults living in Sao Paulo, Brazil. Methods Prospective cohort study using the ``Health, Well-being and Aging{''} (SABE) Study databases of 2006 and 2010. The sample was representative of the community-dwelling older adults living in Sao Paulo, and it is composed of non-frail men and women aged 60 years and older without cognitive decline. We calculated the frailty incidence rate between older adults with and without depressive symptoms and calculated the incidence rate ratio. Multiple analysis was carried out through Poisson regression with robust variance estimation. Results The initial sample (n = 1,109) presented a mean age of 72 years (from 60 to 96) and 61.1% were women. The final sample was composed of 830 individuals, and the mean follow-up time in the study was 3.8 years. After adjusting the model, depressive symptoms did not predict the onset of frailty at follow-up. Conclusion Depressive symptoms were not shown to be a risk factor for frailty among older adults living in Sao Paulo in this study. (AU)