| Full text | |
| Author(s): |
da Silva, Everton M.
[1]
;
de Albuquerque, Danilo Yano
[1]
;
Zukerman-Schpector, Julio
[2]
;
Schwab, Ricardo S.
[1]
Total Authors: 4
|
| Affiliation: | [1] Univ Fed Sao Carlos UFSCar, Dept Quim, Ctr Excellence Res Sustainable Chem CERSusChem, Rodovia Washington Luis, Km 235 SP-310, BR-13565905 Sao Carlos, SP - Brazil
[2] Univ Fed Sao Carlos UFSCar, Dept Quim, Rodovia Washington Luis, Km 235 SP-310, BR-13565905 Sao Carlos, SP - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | ASIAN JOURNAL OF ORGANIC CHEMISTRY; v. 10, n. 5 MAR 2021. |
| Web of Science Citations: | 0 |
| Abstract | |
A practical, and efficient microwave-assisted, three-step Sonogashira cross-coupling/Deacetonation/Cycloaddition sequence has been developed for the synthesis of a variety of 4-aryl-1,2,3-triazoles from readily available starting materials. The important features of this synthetic sequence include the use of inexpensive 2-methyl-3-butyn-2-ol as an acetylene surrogate, 2-Me-THF as a bio-based solvent, short reaction time, good yields, avoiding the isolation of volatile terminal alkynes. (AU) | |
| FAPESP's process: | 14/50249-8 - Green chemistry: sustainable synthetic methods employing benign solvents, safer reagents, and bio-renewable feedstock |
| Grantee: | Arlene Gonçalves Corrêa |
| Support Opportunities: | Research Grants - Research Centers in Engineering Program |
| FAPESP's process: | 13/06558-3 - Asymmetric catalysis: preparation of chiral alcohols and their derivatives from highly functionalized organozinc reagents and application of new chiral ligands supported on magnetic nanoparticles |
| Grantee: | Ricardo Samuel Schwab |
| Support Opportunities: | Regular Research Grants |